{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T23:13:25Z","timestamp":1789600405293,"version":"build-2803163510"},"reference-count":54,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T00:00:00Z","timestamp":1696464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp;amp; Nutrition"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study aims to examine the antimicrobial and antioxidant activities of the aerial parts of\n                    <jats:italic>Chenopodium album<\/jats:italic>\n                    extracts (CAE) prepared with different solvents, and how\n                    <jats:italic>C.\u2009album<\/jats:italic>\n                    ethanol extract protects them against gentamicin\u2010induced nephrotoxicity. Extracts of\n                    <jats:italic>C.\u2009album<\/jats:italic>\n                    aerial parts were obtained from ethanol, water, methanol, chloroform, and hexane solvents. Thirty\u2010two male\n                    <jats:italic>Wistar albino<\/jats:italic>\n                    rats were used and gentamycin\u2010induced nephrotoxicity was utilized as a model. The water extract of\n                    <jats:italic>C.\u2009album<\/jats:italic>\n                    exhibited no antimicrobial effect, whereas the methanol one created the highest zone diameter on\n                    <jats:italic>Bacillus cereus<\/jats:italic>\n                    (26\u2009mm). The methanol extract displayed the highest activity in DPPH and ABTS. The ethanol extract yielded the highest reducing power in the CUPRAC. The water extract had the highest reducing power in the FRAP. Concerning gentamicin\u2010induced renal damage, creatinine and urea levels in the blood were statistically higher in the gentamicin\u2010\n                    <jats:italic>C.\u2009album<\/jats:italic>\n                    group compared to the other groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.05). Urea and creatinine levels of the gentamicin\u2010\n                    <jats:italic>C.\u2009album<\/jats:italic>\n                    group dropped significantly, indicating that the\n                    <jats:italic>C.\u2009album<\/jats:italic>\n                    was effective against renal damage. The sections from kidney tissues in the gentamicin\u2009+\u2009\n                    <jats:italic>C.\u2009album<\/jats:italic>\n                    group mostly exhibited mild glomerular congestion. Hyaline cast, cytoplasmic vacuolization, necrosis, and apoptosis were not observed. Thanks to\n                    <jats:italic>C.\u2009album<\/jats:italic>\n                    treatment, the gentamicin\u2009+\u2009\n                    <jats:italic>C.\u2009album<\/jats:italic>\n                    suffered less histopathological damage than the gentamicin group did. The results of the present study suggest that CAE can be used as a supportive treatment in people undergoing treatment for nephrotoxicity.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.3733","type":"journal-article","created":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T15:40:29Z","timestamp":1696520429000},"page":"8121-8130","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Investigation of antimicrobial and antioxidant activities of\n                    <i>Chenopodium album<\/i>\n                    extracts and their effects on gentamicin nephrotoxicity in rats"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5977-7621","authenticated-orcid":false,"given":"Perihan","family":"Akba\u015f","sequence":"first","affiliation":[{"name":"Karadeniz Advanced Technology Research and Application Center Ondokuz May\u0131s University  Samsun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7213-3601","authenticated-orcid":false,"given":"Elife","family":"Kaya","sequence":"additional","affiliation":[{"name":"Department of Food Processing, Technical Sciences Vocational School Kahramanmaras Sutcu Imam University  Kahramanmaras Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1879-8180","authenticated-orcid":false,"given":"Mustafa","family":"Makav","sequence":"additional","affiliation":[{"name":"Department of Physiology, Veterinary Faculty Kafkas University  Kars Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1530-8529","authenticated-orcid":false,"given":"G\u00fclden","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine Kafkas University  Kars Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,5]]},"reference":[{"issue":"1","key":"e_1_2_10_2_1","first-page":"83","article-title":"Comparison of the nutritive value and biological activities of the acetone, methanol and water extracts of the leaves of Bidens pilosa and Chenopodium album","volume":"68","author":"Adedapo A.","year":"2011","journal-title":"Acta Poloniae Pharmaceutica \u2010 Drug Research"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2014.03.030"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.18038\/estubtda.622224"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.9775\/KVFD.2021.25390"},{"issue":"4","key":"e_1_2_10_6_1","first-page":"401","article-title":"Bitkisel \u00fcr\u00fcnlerin ve g\u0131dalar\u0131n antioksidan kapasitelerinin belirlenmesinde kullan\u0131lan y\u00f6ntemler","volume":"26","author":"Albayrak S.","year":"2010","journal-title":"Erciyes \u00dcniversitesi Fen Bilimleri Enstit\u00fcs\u00fc Dergisi"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278\u20106915(03)00186\u20108"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742\u20107843.2011.00728.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jksus.2023.102813"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/JF048741X"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.18016\/ksutarimdoga.vi.835763"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/1750\u20103841.16555"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.22377\/IJGP.V7I1.297"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/1811199a0"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181ff023e"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.13040\/IJPSR.0975\u20108232.IJP.1(9).545\u201052"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/pca.924"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/np049857q"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378\u20108741(97)00049\u20104"},{"issue":"3","key":"e_1_2_10_20_1","first-page":"197","article-title":"Traditional medicine in the treatment of enteroparasitosis","volume":"16","author":"Giove Nakazawa R. 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