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This study evaluates the short\u2010term effects of Mediterranean, gluten\u2010free, and Mediterranean gluten\u2010free dietary patterns on thyroid function and autoantibody levels of patients. The 40 patients with Hashimoto's thyroiditis included in the study were randomly divided into four groups (defined as gluten\u2010free, Mediterranean, Mediterranean gluten\u2010free, and controls) for 12\u2009weeks. Thyroid function tests, autoantibody levels, and food consumption were recorded at the beginning and end of the study. There was no statistically significant difference in TSH levels of the groups before the intervention, but a statistically significant difference was found afterward (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Free T<jats:sub>3<\/jats:sub> hormone levels showed a statistically significant difference across the groups before and after the intervention (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Free T<jats:sub>3<\/jats:sub> hormone levels increased significantly in all intervention groups after the intervention, with the highest increase in the Mediterranean group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). In the intervention groups, anti\u2010TPO and anti\u2010Tg levels decreased after the intervention; however, this difference was not significant across groups (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). In addition, body weight, body mass index, waist and hip circumference averages decreased significantly in all intervention groups compared with controls (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The study achieved an increase in Free T<jats:sub>3<\/jats:sub> hormone levels in the intervention groups. The most marked difference was seen in the Mediterranean gluten\u2010free diet model, which may be due to the anti\u2010inflammatory effect of both Mediterranean and gluten\u2010free diets and the loss of body weight as a result of the intervention.<\/jats:p>","DOI":"10.1002\/fsn3.3833","type":"journal-article","created":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T13:55:07Z","timestamp":1700574907000},"page":"1180-1188","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Evaluation of the effect of <scp>gluten\u2010free<\/scp> diet and Mediterranean diet on autoimmune system in patients with Hashimoto's thyroiditis"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1757-5084","authenticated-orcid":false,"given":"Mutlu Tu\u00e7e","family":"\u00dclker","sequence":"first","affiliation":[{"name":"Department of Nutrition and Dietetics, Faculty of Health Sciences Ist\u0131\u0307nye University  Istanbul Turkey"},{"name":"Health Sciences Institute Ac\u0131badem Mehmet Al\u0131\u0307 Ayd\u0131nlar University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7982-180X","authenticated-orcid":false,"given":"G\u00f6zde Ar\u0131t\u0131c\u0131","family":"\u00c7olak","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics, Faculty of Health Sciences Ac\u0131badem Mehmet Al\u0131\u0307 Ayd\u0131nlar University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0494-301X","authenticated-orcid":false,"given":"Murat","family":"Ba\u015f","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics, Faculty of Health Sciences Ac\u0131badem Mehmet Al\u0131\u0307 Ayd\u0131nlar University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7783-8130","authenticated-orcid":false,"given":"Mustafa Genco","family":"Erdem","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine Beykent University  Istanbul Turkey"},{"name":"Istinye University Gaziosmanpasa Medicalpark Hospital Istinye University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,20]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/FNUT.2020.583981"},{"key":"e_1_2_9_3_1","unstructured":"Beslenme Bilgi Sistemi (BeB\u0130S 9).2019.Nutrition Information System\u2010BeBiS Version 8.2 Istanbul."},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/A\u20100856\u20101044\/ID\/R2018\u201012\u20100426\u20100027"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/NU10101410"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.26444\/AAEM\/112331"},{"key":"e_1_2_9_7_1","unstructured":"Isak\u2014The International Society for the Advancement of Kinanthropometry.2022https:\/\/www.isak.global\/Home\/Index."},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/S41598\u2010020\u201067719\u20107"},{"key":"e_1_2_9_9_1","unstructured":"Keskink\u0131l\u0131n\u00e7 B. &Yard\u0131m N.(2017).Patient follow\u2010up guide for dietitians weight management manual.https:\/\/hsgm.saglik.gov.tr\/depo\/birimler\/saglikli\u2010beslenme\u2010hareketli\u2010hayat\u2010db\/Haberler\/Diyetisyenler\u2010Izlem\u2010Rehberi\/Diyetisyenler_icin_hasta_izleme_rehberi.pdf"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/A\u20100653\u20107108\/ID\/R06\u20102018\u20100238\u2010ENDO\u20100031"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2011.639084"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/IJMS23126580"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15041041"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/NU13030862"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/JCM10153240"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.BEEM.2019.101367"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.AUTREV.2020.102649"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1089\/THY.2020.0299\/ASSET\/IMAGES\/LARGE\/THY.2020.0299_FIGURE3.JPEG"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/FIMMU.2019.02349"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/NU14091727"},{"key":"e_1_2_9_21_1","unstructured":"World Health Organization (WHO). 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