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Turmeric, a member of Zingiberaceae family, has extensive application worldwide due to its beneficial medicinal attributes and is extensively used as a medicinal plant. Most people use turmeric as a spice, and it is a chief source of polyphenol curcumin.\n                    <jats:italic>Curcuma longa<\/jats:italic>\n                    has therapeutic properties, and since the initial extraction of curcumin from this plant, it has gained prodigious consideration from scientists in the medical field. The biological properties of curcumin, also known as 1,7\u2010bis (4\u2010hydroxy\u20103\u2010methoxyphenyl)\u20101,6\u2010heptadiene\u20103,5\u2010dione, or diferuloylmethane, include anti\u2010inflammatory, anti\u2010oxidant, anti\u2010cancer, anti\u2010asthmatic, anti\u2010arthritic, neuroprotective, anti\u2010diabetic, anti\u2010obesity, wound\u2010healing, hepatoprotective, skin curative, reproductive role, etc. This work has reviewed many clinical trials and their findings about these activities. The focus of this review manuscript is concentrated on the presently existing clinical and animal studies, which exposed the possible anti\u2010retroviral activities of curcumin and its by\u2010products.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.4469","type":"journal-article","created":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T09:58:53Z","timestamp":1727258333000},"page":"8623-8650","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["On the health effects of curcumin and its derivatives"],"prefix":"10.1002","volume":"12","author":[{"given":"Hudda","family":"Ayub","sequence":"first","affiliation":[{"name":"National Institute of Food Science &amp; Technology University of Agriculture  Faisalabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahad","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Food Science and Technology Muhammad Nawaz Shareef University of Agriculture  Multan Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munnaza","family":"Saeed","sequence":"additional","affiliation":[{"name":"National Institute of Food Science &amp; Technology University of Agriculture  Faisalabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Husnat","family":"Ahmad","sequence":"additional","affiliation":[{"name":"National Institute of Food Science &amp; Technology University of Agriculture  Faisalabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4253-2796","authenticated-orcid":false,"given":"Fahad","family":"Al\u2010Asmari","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition Sciences, College of Agricultural and Food Sciences King Faisal University  Al\u2010Ahsa Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Fawzy","family":"Ramadan","sequence":"additional","affiliation":[{"name":"Department of Clinical Nutrition, Faculty of Applied Medical Sciences Umm Al\u2010Qura University  Makkah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Alissa","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory, College of Applied Medical Sciences Prince Sattam bin Abdulaziz University  Al\u2010Kharj Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Adnan","family":"Arif","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences for Animal Health and Food Safety University of Turin  Torino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Umair Jamil","family":"Rana","sequence":"additional","affiliation":[{"name":"National Institute of Food Science &amp; Technology University of Agriculture  Faisalabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Subtain","sequence":"additional","affiliation":[{"name":"National Institute of Food Science &amp; Technology University of Agriculture  Faisalabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Abdul","family":"Rahim","sequence":"additional","affiliation":[{"name":"Department of Food Science &amp; Nutrition, Faculty of Medicine and Allied Health Sciences Times Institute  Multan Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9885-8301","authenticated-orcid":false,"given":"Eliasse","family":"Zongo","sequence":"additional","affiliation":[{"name":"Laboratoire de Recherche et d'Enseignement en Sant\u00e9 et Biotechnologies Animales Universit\u00e9 Nazi BONI  Bobo Dioulasso Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3151-0276","authenticated-orcid":false,"given":"Nazir","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences Government College University Faisalabad  Faisalabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,24]]},"reference":[{"issue":"2","key":"e_1_2_11_2_1","first-page":"379","article-title":"Protective effects of diallyl sulfide and curcumin separately against thallium\u2010induced toxicity in rats","volume":"17","author":"Abdel\u2010Daim M. 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