{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T12:13:44Z","timestamp":1788437624967,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T00:00:00Z","timestamp":1750982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T00:00:00Z","timestamp":1750982400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004320","name":"Shiraz University of Medical Sciences","doi-asserted-by":"publisher","award":["28537"],"award-info":[{"award-number":["28537"]}],"id":[{"id":"10.13039\/501100004320","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp;amp; Nutrition"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study aimed to determine the effects of daily consumption of fortified yogurt on the metabolic health parameters in women with PCOS. In this randomized double\u2010blind controlled trial, participants received either yogurt fortified with 10\n                    <jats:sup>6<\/jats:sup>\n                    \u2009CFU\/g probiotics, 1000\u2009IU vitamin D, and 50\u2009IU vitamin E in the intervention group (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200945) or plain yogurt in the control group (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200945) for 8\u2009weeks. The group that consumed fortified yogurt demonstrated a significant reduction in homeostatic model assessment for insulin resistance (HOMA\u2010IR) (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.040), high\u2010sensitivity C\u2010reactive protein (Hs\u2010CRP) (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.012), malondialdehyde (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.020), and total testosterone (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.042), along with an increase in serum levels of 25(OH) D (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.003) and alpha\u2010tocopherol (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.020) compared to the control group. Nevertheless, further research is required to confirm the efficacy of this functional food as an adjunctive therapy for addressing metabolic health issues in PCOS patients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Trial Registration:<\/jats:bold>\n                    The Iranian Registry of Clinical Trials (IRCT20231210060323N1)\n                  <\/jats:p>","DOI":"10.1002\/fsn3.70506","type":"journal-article","created":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T08:03:41Z","timestamp":1751011421000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Effects of a Novel Fortified Dairy Product on Weight Loss, Metabolic Profiles, and Endocrine Hormones in Women With Polycystic Ovary Syndrome: A Double\u2010Blind Randomized Controlled Trial"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4534-589X","authenticated-orcid":false,"given":"Moein","family":"Askarpour","sequence":"first","affiliation":[{"name":"Department of Clinical Nutrition, School of Nutrition and Food Sciences Shiraz University of Medical Sciences  Shiraz Iran"},{"name":"Students' Research Committee, School of Nutrition and Food Science Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahia Namavar","family":"Jahromi","sequence":"additional","affiliation":[{"name":"Infertility Research Center Shiraz University of Medical Sciences  Shiraz Iran"},{"name":"Department of OB\u2010GYN, School of Medicine Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Hadi","family":"Eskandari","sequence":"additional","affiliation":[{"name":"Department of Food Science and Technology, School of 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