{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:44:53Z","timestamp":1786977893674,"version":"build-2736575974"},"reference-count":57,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T00:00:00Z","timestamp":1755043200000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp;amp; Nutrition"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study evaluates the antidiabetic, anti\u2010Alzheimer, antimicrobial, and antioxidant activities of water and methanol extracts, as well as essential oils, from\n                    <jats:italic>Satureja macrantha<\/jats:italic>\n                    and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Satureja hortensis<\/jats:italic>\n                    <\/jats:styled-content>\n                    . Chemical characterization was conducted using LC\u2013MS\/MS for phenolic profiles and GC\u2013MS for essential oil composition. Biological activities were assessed via DPPH\u02d9 and ABTS\u02d9\n                    <jats:sup>+<\/jats:sup>\n                    assays for antioxidant capacity, \u03b1\u2010glucosidase and \u03b1\u2010amylase inhibition for antidiabetic potential, cholinesterase inhibition for anti\u2010Alzheimer activity, and the microdilution method for antimicrobial effects. Genotoxicity and antigenotoxicity were evaluated using Ames and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Allium cepa<\/jats:italic>\n                    <\/jats:styled-content>\n                    assays. Rosmarinic acid was most abundant in\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S. macrantha<\/jats:italic>\n                    <\/jats:styled-content>\n                    water extract (50.687.02\u2009ng\/mL), while thymol (45.1%) and p\u2010cymene (45.8%) were identified as major oil components.\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S. hortensis<\/jats:italic>\n                    <\/jats:styled-content>\n                    essential oil showed the strongest \u03b1\u2010glucosidase (41.33%) and butyrylcholinesterase inhibition (35.68%), whereas\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S. macrantha<\/jats:italic>\n                    <\/jats:styled-content>\n                    oil exhibited higher acetylcholinesterase inhibition (16.05%). Antioxidant activity was most pronounced in\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S. macrantha<\/jats:italic>\n                    <\/jats:styled-content>\n                    water extract (ABTS\n                    <jats:sup>\u02d9+<\/jats:sup>\n                    : 52.11%, DPPH\u02d9: 28.76%).\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S. hortensis<\/jats:italic>\n                    <\/jats:styled-content>\n                    essential oil demonstrated the most effective antimicrobial properties. These findings suggest that both\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S. macrantha<\/jats:italic>\n                    <\/jats:styled-content>\n                    and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S. hortensis<\/jats:italic>\n                    <\/jats:styled-content>\n                    could be recommended as safe and effective candidates for use in the development of natural therapeutic agents.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.70733","type":"journal-article","created":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T11:53:04Z","timestamp":1755085984000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Phytochemical Traits and Biological Activity of\n                    <i>Satureja hortensis<\/i>\n                    and\n                    <i>Satureja macrantha<\/i>\n                    as Culinary Spices Using\n                    <scp>GC<\/scp>\n                    \u2013\n                    <scp>MS<\/scp>\n                    \/\n                    <scp>MS<\/scp>\n                    and\n                    <scp>LC<\/scp>\n                    \u2013\n                    <scp>MS<\/scp>\n                    \/\n                    <scp>MS<\/scp>\n                    Techniques"],"prefix":"10.1002","volume":"13","author":[{"given":"Pardis","family":"Elmdoustazar","sequence":"first","affiliation":[{"name":"Faculty of Pharmacy, Department of Pharmacognosy Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilge","family":"Ayd\u0131n","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Department of Pharmacognosy Erzincan Binali Y\u0131ld\u0131r\u0131m University  Erzincan T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"\u00d6nal","sequence":"additional","affiliation":[{"name":"Eastern Anatolia Forestry Research Institute  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hafize","family":"Yuca","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Department of Pharmacognosy Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Karaday\u0131","sequence":"additional","affiliation":[{"name":"Faculty of Science, Department of Biology Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuf","family":"G\u00fcl\u015fahin","sequence":"additional","affiliation":[{"name":"Faculty of Science, Department of Biology Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bet\u00fcl","family":"Demirci","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Department of Pharmacognosy Anadolu University  Eski\u015fehir T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3268-721X","authenticated-orcid":false,"given":"Song\u00fcl","family":"Karakaya","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Department of Pharmaceutical Botany Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z\u00fchal","family":"G\u00fcvenalp","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Department of Pharmacognosy Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,13]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods9040494"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/10826076.2022.2029745"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/0972060X.2007.10643532"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.30492\/ijcce.2018.32113"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.3c07289"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.3653552"},{"issue":"4","key":"e_1_2_13_8_1","first-page":"267","article-title":"Screening of Fifteen Indian Ayurvedic Plants for Alpha\u2010Glucosidase Inhibitory Activity and Enzyme Kinetics","volume":"3","author":"Bachhawat J. 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