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This review examines the overlapping processes between FA and obesity, with a focus on the opioid and dopamine reward systems. Sweet, fatty, and salty processed foods dominate our brain pathways, making them increasingly less able to feel full and urge us to eat more than we require. While the diagnosis remains controversial, the Yale Food Addiction Scale (YFAS) is the most widely used assessment instrument. Potential management options include nutrition\u2010based interventions, such as whole\u2010food diets, and behavioral strategies, such as cognitive\u2010behavioral therapy (CBT) and conscious eating. However, stigmatization, labeling, and food industry promotion of addictive products pose ethical concerns. Against the backdrop of ongoing controversy, this article summarizes the highest\u2010quality research available on the neurological basis of FA as well as its measurement challenges and possible therapeutic options. The public health implications of FA and obesity can be lessened by future research to explore personalized treatments, refine diagnostic systems, and inform policy.<\/jats:p>","DOI":"10.1002\/fsn3.70799","type":"journal-article","created":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T13:59:23Z","timestamp":1755266363000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Comparative Analysis of Food Addiction and Obesity: A Critical Review"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6650-9203","authenticated-orcid":false,"given":"Sammra","family":"Maqsood","sequence":"first","affiliation":[{"name":"National Institute of Food Science and Technology University of Agriculture Faisalabad  Faisalabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faiyaz","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Basic Health Sciences, College of Applied Medical Sciences Qassim University  Buraydah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5290-7631","authenticated-orcid":false,"given":"Muhammad Tayyab","family":"Arshad","sequence":"additional","affiliation":[{"name":"Functional Food and Nutrition Program, Faculty of Agro\u2010Industry Prince of Songkla University  Hatyai Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2893-4249","authenticated-orcid":false,"given":"Ali","family":"Ikram","sequence":"additional","affiliation":[{"name":"University Institute of Food Science and Technology The University of Lahore  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammed Adem","family":"Abdullahi","sequence":"additional","affiliation":[{"name":"Department of Food Science and Postharvest Technology Jimma University College of Agriculture and Veterinary Medicine, Jimma University  Jimma Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,15]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11092086"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.2595"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/nuf.12662"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.70689"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2023.03.002"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2016.9"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-019-0176-8"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612823666170823101713"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2015.00744"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.appet.2015.01.008"},{"key":"e_1_2_15_12_1","first-page":"589","article-title":"Food Labeling Disclosures and the Commercial Speech Doctrine: Combating America's Growing Problem","volume":"61","author":"Brown L. 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