{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:08:07Z","timestamp":1790172487424,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp;amp; Nutrition"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Artemisiae argyi<\/jats:italic>\n                    Folium (AAF) is a traditional medicinal and edible material. However, the pharmacologically active compounds and quality control of AAF have not been fully investigated. To solve these problems, we developed a novel method based on HPLC\u2010Q\u2010Exactive Orbitrap\u2010HRMS for rapid identification of chemical compounds in AAF. Forty\u2010five compounds were identified tentatively, mostly consisting of flavonoids and phenylpropanoids, and their fragmentation pathways were elucidated. Additionally, we present the first report on the HPLC\u2010UV fingerprints of AAF from genuine production areas, combined with chemometric analysis to elucidate the differences in the quality of AAF from different regions. Our results showed significant differences in the compounds of AAF from different production areas, and these variations could lead to inconsistencies in quality during large\u2010scale production. To ensure quality stability during the actual production process, it is essential to establish a method for rapid quantification of markers representing the potential differences in AAF quality. In this study, we developed a novel method called quantitative analysis of multicomponents by single marker for the simultaneous measurement of six phenylpropanoids and two flavonoids. Our study provides an analytical method and scientific basis for the standardized production, component analysis, and quality control of AAF as a functional food raw material.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.70856","type":"journal-article","created":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T11:22:36Z","timestamp":1756725756000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Research on Material Basis and Quality Control of\n                    <i>Artemisiae argyi<\/i>\n                    Folium, a Traditional Medicinal and Edible Material"],"prefix":"10.1002","volume":"13","author":[{"given":"Feifei","family":"Xie","sequence":"first","affiliation":[{"name":"Guangzhou University of Traditional Chinese Medicine  Guangzhou China"},{"name":"Guangdong Yifang Pharmaceutical co., Ltd. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula  Foshan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cong","family":"Ye","sequence":"additional","affiliation":[{"name":"Guangzhou University of Traditional Chinese Medicine  Guangzhou China"},{"name":"Guangdong Yifang Pharmaceutical co., Ltd. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula  Foshan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibao","family":"Qiu","sequence":"additional","affiliation":[{"name":"Guangzhou University of Traditional Chinese Medicine  Guangzhou China"},{"name":"Guangdong Yifang Pharmaceutical co., Ltd. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula  Foshan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoying","family":"Lu","sequence":"additional","affiliation":[{"name":"Guangdong Yifang Pharmaceutical co., Ltd. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula  Foshan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyuan","family":"Qu","sequence":"additional","affiliation":[{"name":"Guangdong Yifang Pharmaceutical co., Ltd. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula  Foshan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhizhou","family":"Ling","sequence":"additional","affiliation":[{"name":"College of Food Science South China Agricultural University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyu","family":"Li","sequence":"additional","affiliation":[{"name":"Guangdong Yifang Pharmaceutical co., Ltd. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula  Foshan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongmei","family":"Sun","sequence":"additional","affiliation":[{"name":"Guangdong Yifang Pharmaceutical co., Ltd. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula  Foshan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minyou","family":"He","sequence":"additional","affiliation":[{"name":"Guangdong Yifang Pharmaceutical co., Ltd. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula  Foshan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Guangdong Yifang Pharmaceutical co., Ltd. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula  Foshan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9450-3359","authenticated-orcid":false,"given":"Wenhui","family":"Luo","sequence":"additional","affiliation":[{"name":"Guangdong Yifang Pharmaceutical co., Ltd. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula  Foshan China"},{"name":"Jiangxi Yifang Tianjiang Pharmaceutical co., Ltd.  Nanchang China"},{"name":"School of Chinese Materia Medica Guangdong Pharmaceutical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,1]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules17032542"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2018.03.032"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.48130\/mpb\u20100024\u20100002"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2019.125937"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27185842"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2017.08.021"},{"key":"e_1_2_9_8_1","first-page":"480","volume-title":"Pharmacopoeia of the People's Republic of China 2020(Volume IV)","author":"Jiao H.","year":"2020"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19051387"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2022.111937"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.201900365"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/pca.3261"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s44403\u2010025\u201000026\u2010z"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2021.108614"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2018.11.029"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/8042631"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2024.116222"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4531092"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00210\u2010024\u201003122\u20107"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2022.128531"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11101\u2010023\u201009910\u2010y"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2019.103268"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/6067647"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1166\/jbmb.2023.2306"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568026623666230330152345"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28052022"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/7178982"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2021.114090"}],"container-title":["Food Science &amp; Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/fsn3.70856","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/fsn3.70856","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/fsn3.70856","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:45:46Z","timestamp":1790171146000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/fsn3.70856"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1002\/fsn3.70856"],"URL":"https:\/\/doi.org\/10.1002\/fsn3.70856","archive":["Portico"],"relation":{},"ISSN":["2048-7177","2048-7177"],"issn-type":[{"value":"2048-7177","type":"print"},{"value":"2048-7177","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"2025-04-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70856"}}