{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:08:07Z","timestamp":1790168887860,"version":"4.1.0"},"reference-count":61,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:00:00Z","timestamp":1761091200000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp;amp; Nutrition"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study explores the chemical composition, antimicrobial, and antioxidant properties of essential oils derived from\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Lepidium sativum<\/jats:italic>\n                    <\/jats:styled-content>\n                    seeds, collected from Legambo, Jama, and Tenta districts. Notably, the oils were predominantly composed of benzyl nitrile, alongside sulfur\u2010containing compounds like trisulfide bis(phenylmethyl) and disulfide bis(phenylmethyl). The essential oil yield varied between 2.3% and 3.8%, with the Tenta sample yielding the highest amount. The oils demonstrated significant antimicrobial activity, with inhibition zones ranging from 27.2 to 36.8\u2009mm and minimum inhibitory concentration (MIC) values of 1.26\u20133.00\u2009mg\/mL for bacterial strains and 2.01\u20132.62\u2009mg\/mL for fungal strains. Remarkably, the strongest antimicrobial effect was against\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    <\/jats:styled-content>\n                    (MIC\u2009=\u20091.26\u2009mg\/mL) and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Candida albicans<\/jats:italic>\n                    <\/jats:styled-content>\n                    (MIC\u2009=\u20092.01\u2009mg\/mL). Additionally, the essential oils exhibited robust antioxidant potential, with the oil from the Tenta district showing the highest activity, as indicated by an IC\n                    <jats:sub>50<\/jats:sub>\n                    value of 11.31\u2009\u00b1\u20090.01\u2009\u03bcg\/mL in the DPPH radical scavenging assay. Significant variations in essential oil composition and bioactivity were observed across districts, suggesting that environmental factors such as soil type, climate, and altitude play critical roles in shaping these differences. This study not only highlights the therapeutic potential of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>L. sativum<\/jats:italic>\n                    <\/jats:styled-content>\n                    essential oils in antimicrobial and antioxidant applications but also underscores the importance of investigating district\u2010specific variations and the commercial viability of these bioactive components. The findings provide a novel contribution to the understanding of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>L. sativum<\/jats:italic>\n                    <\/jats:styled-content>\n                    's bioactive properties and their implications for health and industry.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.71119","type":"journal-article","created":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T12:18:47Z","timestamp":1761135527000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Compositions, Antimicrobial, and Antioxidant Activities of the Essential Oil Extracted From Garden Cress Seeds Growing in Three Districts of South Wollo, Ethiopia"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3045-9245","authenticated-orcid":false,"given":"Melese Damtew","family":"Asfaw","sequence":"first","affiliation":[{"name":"College of Natural and Computational Science Mekdela Amba University  Tulu Awuliya Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mequanint Gebeyehu","family":"Awoke","sequence":"additional","affiliation":[{"name":"College of Natural and Computational Science Mekdela Amba University  Tulu Awuliya Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adamu Tizazu","family":"Yadeta","sequence":"additional","affiliation":[{"name":"College of Natural and Computational Science Mekdela Amba University  Tulu Awuliya Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,22]]},"reference":[{"issue":"5","key":"e_1_2_8_2_1","first-page":"1685","article-title":"Antioxidant and Antibacterial Properties of Different Extracts of Garden Cress (Lepidium sativum L.)","volume":"43","author":"Abo El\u2010Maati M. 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