{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T07:08:21Z","timestamp":1788246501393,"version":"build-2803163510"},"reference-count":47,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T00:00:00Z","timestamp":1765584000000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp;amp; Nutrition"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The production of saffron (\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Crocus sativus<\/jats:italic>\n                    <\/jats:styled-content>\n                    L.) generates large quantities of floral by\u2010products, particularly stamens, which are often discarded despite their potential as sources of bioactive compounds. This study aimed to provide, for the first time, a comprehensive and comparative characterization of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>C. sativus<\/jats:italic>\n                    <\/jats:styled-content>\n                    stamen extracts and fractions using a multianalytical approach (UHPLC\u2013MS\/MS, GC\u2013MS, ICP\u2010OES, and spectrophotometry), in order to reveal their nutritional, phytochemical, and antioxidant potential. Elemental analyses revealed high levels of essential macro\u2010 and micronutrients such as potassium, phosphorus, calcium, and iron. Spectrophotometric and chromatographic assays quantified sugars and proteins, while UHPLC\u2013MS\/MS and HPLC\u2010DAD identified key phenolic acids and flavonoids, including chlorogenic acid, rutin, quercetin, and crocin. GC\u2013MS profiling of the petroleum ether fraction showed palmitic and oleic acids as major components. The hydrolyzed ethyl acetate fraction displayed the highest antioxidant activity across DPPH, ABTS, \u03b2\u2010carotene bleaching, and metal\u2010chelating assays, likely due to the release of aglycone phenolics and synergistic effects. This work introduces an original integrative analysis of saffron stamens, highlighting them as an underexplored and sustainable source of bioactive nutrients and antioxidants with promising applications in the food, nutraceutical, and cosmetic industries.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.71282","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T10:32:23Z","timestamp":1765621943000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["From Floral By\u2010Product to Bioactive Resource: Phytochemical Profiling and Antioxidant Potential of\n                    <i>Crocus sativus<\/i>\n                    Stamens"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6149-0638","authenticated-orcid":false,"given":"Samira","family":"Mamri","sequence":"first","affiliation":[{"name":"Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Department of Biology, Faculty of Sciences Mohammed First University  Oujda Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanae","family":"Baddaoui","sequence":"additional","affiliation":[{"name":"Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Department of Biology, Faculty of Sciences Mohammed First University  Oujda Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilaycan","family":"\u00c7am","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Sciences Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University  Mu\u011fla T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cansel","family":"\u00c7akir","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Sciences Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University  Mu\u011fla 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Chemistry, Faculty of Sciences Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University  Mu\u011fla T\u00fcrkiye"},{"name":"Faculty of Medicine and Pharmacy Mohammed First University  Oujda Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9275-5061","authenticated-orcid":false,"given":"Mohammed","family":"Choukri","sequence":"additional","affiliation":[{"name":"Maternal\u2010Child and Mental Health Research Laboratory, Faculty of Medicine and Pharmacy Mohammed First University  Oujda Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0685-8243","authenticated-orcid":false,"given":"Musaab","family":"Dauelbait","sequence":"additional","affiliation":[{"name":"University of Bahr el Ghazal  Wau South Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gehan M.","family":"Elossaily","sequence":"additional","affiliation":[{"name":"Department of Basic Medical Sciences, College of Medicine AlMaarefa University  Riyadh Saudi Arabia"},{"name":"Research Center, Deanship of Scientific Research and Post\u2010Graduate Studies AlMaarefa University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yousef A.","family":"Bin Jardan","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, College of Pharmacy King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdel\u2010Rhman Z.","family":"Gaafar","sequence":"additional","affiliation":[{"name":"Department of Botany and Microbiology, College of Science King Saud University  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdeslam","family":"Asehraou","sequence":"additional","affiliation":[{"name":"Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Department of Biology, Faculty of Sciences Mohammed First University  Oujda 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