{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T12:11:56Z","timestamp":1789992716223,"version":"4.0.1"},"reference-count":63,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Moringa oleifera<\/jats:italic>\n                    <\/jats:styled-content>\n                    is suggested as an antihypertensive and anti\u2010obesity agent, but there is insufficient evidence to establish a causal link between\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Moringa oleifera<\/jats:italic>\n                    <\/jats:styled-content>\n                    and reductions in blood pressure and body measurements in humans. This systematic review and meta\u2010analysis seek to examine the effects of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Moringa oleifera<\/jats:italic>\n                    <\/jats:styled-content>\n                    on body weight and blood pressure. A search was conducted through Web of Science, Scopus, and PubMed, along with a manual review of bibliographies, for articles published up to July 2024. Out of 2295 articles, eight randomized controlled trials (RCTs) were included. The results indicated that\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Moringa oleifera<\/jats:italic>\n                    <\/jats:styled-content>\n                    consumption significantly reduced systolic blood pressure (SBP) by weighted mean differences (WMDs): \u22126.00\u2009mmHg,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001 and diastolic blood pressure (DBP) by WMD: \u22127.32\u2009mmHg,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001. However, no significant changes were observed in body mass index (BMI) (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.435) and body weight (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.938) compared to those who did not consume\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Moringa oleifera<\/jats:italic>\n                    <\/jats:styled-content>\n                    . Subgroup analyses revealed that SBP significantly decreased in adults consuming 5\u201310\u2009g\/day of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Moringa oleifera<\/jats:italic>\n                    <\/jats:styled-content>\n                    , particularly in individuals with a BMI below 29.9 and those treated for more than 4\u2009weeks. Furthermore,\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Moringa oleifera<\/jats:italic>\n                    <\/jats:styled-content>\n                    intake was linked to a significant reduction in DBP among participants taking &lt;\u200910\u2009g\/day, those who were overweight, and individuals who supplemented for over 4\u2009weeks. Our systematic review and meta\u2010analysis of RCT indicated that\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Moringa oleifera<\/jats:italic>\n                    <\/jats:styled-content>\n                    had a significant impact on blood pressure, but it did not affect body weight or BMI. Further research is necessary to confirm these findings.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.71899","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T07:40:51Z","timestamp":1779435651000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Effect of\n                    <scp>\n                      <i>Moringa oleifera<\/i>\n                    <\/scp>\n                    on Body Weight and Blood Pressure: A Systematic Review and Meta\u2010Analysis of Randomized Controlled Trials"],"prefix":"10.1002","volume":"14","author":[{"given":"Mahnoush Mehrzad","family":"Samarin","sequence":"first","affiliation":[{"name":"Department of Physical Education and Sport Sciences, Science and Research Branch Islamic Azad University  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Sheikhhossein","sequence":"additional","affiliation":[{"name":"Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics Tehran University of Medical Sciences (TUMS)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir Hossein","family":"Khalilkhaneh","sequence":"additional","affiliation":[{"name":"Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics Tehran University of Medical Sciences (TUMS)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shadi","family":"Ghaemi","sequence":"additional","affiliation":[{"name":"Department of Community Nutrition, School of Nutritional Sciences and Dietetics Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amin","family":"Abbasi","sequence":"additional","affiliation":[{"name":"Department of Food Science and Technology, Faculty of Nutrition and Food Sciences Tabriz University of Medical Sciences  Tabriz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadi","family":"Bazyar","sequence":"additional","affiliation":[{"name":"Department of Public Health Sirjan School of Medical Sciences  Sirjan Iran"},{"name":"Student Research Committee Sirjan School of Medical Sciences  Sirjan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farhang","family":"Djafari","sequence":"additional","affiliation":[{"name":"School of Health, Medical and Applied Sciences Central Queensland University  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Dianati","sequence":"additional","affiliation":[{"name":"Department of Clinical Nutrition &amp; Dietetics, National Nutrition &amp; Food Technology Research Institute Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Mojtaba","family":"Khodashenas","sequence":"additional","affiliation":[{"name":"Student Research Committee, Department of Clinical Nutrition &amp; Dietetics, National Nutrition &amp; Food Technology Research Institute Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1194-9687","authenticated-orcid":false,"given":"Gholamreza","family":"Askari","sequence":"additional","affiliation":[{"name":"Nutrition and Food Security Research Center Isfahan University of Medical Sciences  Isfahan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0640-2142","authenticated-orcid":false,"given":"Mohammad Reza","family":"Amini","sequence":"additional","affiliation":[{"name":"Nutrition and Food Security Research Center Isfahan University of Medical Sciences  Isfahan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1139\/bcb-2014-0081"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2014.15.20.8571"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/23312025.2019.1596526"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/10641963.2020.1714640"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110605"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/02601060231176873"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.5455\/jabet.2019.d28"},{"key":"e_1_2_12_9_1","first-page":"1","article-title":"Role of Nutraceuticals in the Prevention and Treatment of Hypertension and Cardiovascular Diseases","volume":"5","author":"Alves Q. 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