{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T21:20:24Z","timestamp":1787606424924,"version":"build-2736575974"},"reference-count":222,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Intracerebral hemorrhage (ICH) is one of the most devastating subtypes of stroke, with limited preventive options and a challenging recovery process. This study presents a translational framework that integrates tea polyphenols (TPPs) and exercise\u2010induced metabolites as dual modulators of neurovascular stability, with a focus on patient education for enhancing post\u2010stroke recovery. By synthesizing preclinical and clinical evidence, we demonstrate how TPPs, particularly epigallocatechin gallate (EGCG), and key exercise metabolites such as lactate, \u03b2\u2010hydroxybutyrate, and short\u2010chain fatty acids (SCFAs) interact with shared redox\u2010sensitive and inflammatory signaling pathways (Nrf2\/NF\u2010\u03baB\/AMPK axis) to reinforce endothelial integrity, preserve blood\u2013brain barrier function, and maintain cerebral perfusion. These interventions also reshape the gut microbiota, promoting an SCFA\u2010enriched, anti\u2010inflammatory profile that fosters bidirectional gut\u2010brain communication, further stabilizing vascular homeostasis. Multi\u2010omics evidence suggests that TPPs and exercise metabolites may jointly regulate metabolic and immune pathways, enhancing resilience against oxidative and inflammatory injuries in the vasculature. We propose a mechanistic model in which TPPs and exercise\u2010derived metabolites synergistically support neurovascular function and reduce neurovascular vulnerability associated with ICH, while promoting cognitive recovery and metabolic health. Incorporating these findings into patient rehabilitation education may help individuals make informed decisions about lifestyle changes that enhance vascular health. Future research should explore the dose\u2013response relationship, the optimal timing between tea and exercise, and individual variations, using metabolomic, microbiomic, and imaging biomarkers to personalize cerebrovascular prevention strategies.<\/jats:p>","DOI":"10.1002\/fsn3.72015","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T09:06:16Z","timestamp":1782464776000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Integrating Bone\u2010Brain Axis Modulation and Tea Consumption for Enhancing Neurovascular Resilience and Patient Rehabilitation Education"],"prefix":"10.1002","volume":"14","author":[{"given":"Yazhen","family":"Zhang","sequence":"first","affiliation":[{"name":"Ningde Normal University  Ningde China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6122-2227","authenticated-orcid":false,"given":"Yisheng","family":"Chen","sequence":"additional","affiliation":[{"name":"Ningde Normal University  Ningde China"},{"name":"Fujian Key Laboratory of Toxicant and Drug Toxicology Medical College, Ningde Normal University  Ningde China"},{"name":"Department of Vascular and Interventional Radiology Ningde Municipal Hospital of Ningde Normal University  Ningde China"},{"name":"Ningde Clinical Medical College of Fujian Medical University  Ningde Fujian Province China"},{"name":"Fujian Key Laboratory of Medical Bioinformatics Fujian Medical University  Fuzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoyuan","family":"Huang","sequence":"additional","affiliation":[{"name":"Ningde Normal University  Ningde China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shizhong","family":"Zheng","sequence":"additional","affiliation":[{"name":"Ningde Normal University  Ningde China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengwan","family":"Shen","sequence":"additional","affiliation":[{"name":"Ningde Normal University  Ningde China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiangqiang","family":"Wang","sequence":"additional","affiliation":[{"name":"Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Chen","sequence":"additional","affiliation":[{"name":"Faculty of Science Universiti Malaya  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9552-4389","authenticated-orcid":false,"given":"Shiwei","family":"He","sequence":"additional","affiliation":[{"name":"Institute of Population Medicine, School of Public Health Fujian Medical University  Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Yang","sequence":"additional","affiliation":[{"name":"Vegetable Science, College of Horticulture Gansu Agricultural University  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zemin","family":"Ou","sequence":"additional","affiliation":[{"name":"China Academy of Chinese Medical Sciences Institute of Chinese Materia Medica  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1365-3927","authenticated-orcid":false,"given":"Zijin","family":"Sun","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7182-6075","authenticated-orcid":false,"given":"Yuzhen","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation The Second Affiliated Hospital of Shandong First Medical University  Taian Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6149-7057","authenticated-orcid":false,"given":"Guanghui","family":"Wu","sequence":"additional","affiliation":[{"name":"Ningde Clinical Medical College of Fujian Medical University  Ningde Fujian Province China"},{"name":"Department of Neurosurgery Ningde Clinical Medical College of Fujian Medical University  Ningde Fujian Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0568-0645","authenticated-orcid":false,"given":"Lei","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Molecular Cell and Cancer Biology University of Massachusetts Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Department of Physiology and Pharmacology, Department of Neurosurgery and Anesthesiology School of Medicine, Loma Linda University  Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zui","family":"Zou","sequence":"additional","affiliation":[{"name":"School of Anesthesiology Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wangzheqi","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Anesthesiology Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaocong","family":"Zhao","sequence":"additional","affiliation":[{"name":"Xiamen University of Technology  Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,26]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2011.01.002"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25063521"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.92888"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfbc.14397"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2023.12.008"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2023.115820"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.2478\/acb\u20102022\u20100021"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.22074\/cellj.2016.4714"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.34133\/research.0327"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/2037838"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1201\/b17442-9"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crphys.2022.06.002"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2023.1223411"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.9734\/EJNFS\/2015\/12712"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/a\u20101524\u20102095"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40279\u2010018\u20100998\u2010x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/09637486.2022.2150152"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1159\/000489447"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2023.1025936"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.REO.0000000000000186"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.2174\/187152410793429728"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.13005\/bpj\/1199"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/icb.2015.97"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13828"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2024.139140"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfbc.12415"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.70341"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1152\/physiol.00021.2024"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf302477y"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14245234"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2023.1292673"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2019.02.016"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.24976\/Discov.Med.202436186.128"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.85031"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.12944\/CRNFSJ.10.2.5"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.15212\/bioi\u20102025\u20100073"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu9080917"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.16966\/2470\u20106086.174"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2016.10.003"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.13732"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/burnst\/tkad020"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1051\/medsci\/20163206022"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.121.037343"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2011.06.006"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.22038\/ijbms.2021.52980.11943"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1089\/dna.2018.4348"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1800252"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11061709"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.34133\/research.0464"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12603\u2010012\u20100077\u20101"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12452"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjpad.2025.100271"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.10598"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1080\/09735070.2012.11886434"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmgh.2021.02.007"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2007.02.001"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23094652"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.6b04538"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15153454"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00014.2016"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12986\u2010024\u201000880\u20102"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6432"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01434.2010"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015\u20103351"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408690390826464"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2020.108478"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2012.06.017"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports\u20102017\u2010097965"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfbc.13870"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.30958\/ajspo.3.4.2"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2018.03.019"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2022.113594"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.944195"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43657\u2010024\u201000179\u20105"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.656455"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/7432797"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.2463\/mrms.rev.2024\u20100013"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241713114"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25010124"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.780602"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2020.153338"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.622507"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2025.142932"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.53388\/TMR20230512002"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.5009\/gnl.2012.6.2.188"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394\u2010014\u20100757\u20101"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2011.03.010"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12010160"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu7042839"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods13081167"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.2174\/13816128113196660751"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26010085"},{"key":"e_1_2_12_94_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.3c08184"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.1080\/10715762.2019.1612059"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.1093\/cdn\/nzaa045_053"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0277453"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.1139\/apnm\u20102014\u20100538"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40246\u2010023\u201000561\u2010w"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu16101500"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40618\u2010021\u201001551\u20102"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003\u20104819\u2010144\u20102\u2010200601170\u201000004"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiosc.2022.12.001"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1159\/000381267"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2024.101237"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.752833"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tice.2025.102998"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035\u2010018\u20101283\u20106"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1123\/ijsnem.2015\u20100293"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1080\/16546628.2017.1333390"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2021.105420"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1080\/10641963.2024.2373467"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1080\/10641963.2025.2503805"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.0c01947"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43657\u2010023\u201000095\u20100"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.0c03587"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tifs.2023.01.013"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2FO00994C"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/825928"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2017.07.008"},{"key":"e_1_2_12_121_1","doi-asserted-by":"publisher","DOI":"10.2174\/157488912803252005"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep46501"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20215249"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmgh.2018.04.003"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nic.2019.03.004"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells8080793"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1113\/EP091856"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/857142"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389201015666140617100945"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19010218"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0096013"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2018.00135"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.2174\/1871523015666160915154443"},{"key":"e_1_2_12_134_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2013.00051"},{"key":"e_1_2_12_135_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0195753"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12906\u2010019\u20102545\u20101"},{"key":"e_1_2_12_137_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.00277"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12970\u2010020\u201000361\u2010w"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232315054"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20153630"},{"key":"e_1_2_12_141_1","doi-asserted-by":"publisher","DOI":"10.2165\/11594400\u2010000000000\u201000000"},{"key":"e_1_2_12_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2015.04.002"},{"key":"e_1_2_12_143_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7FO00991G"},{"key":"e_1_2_12_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jshs.2022.10.003"},{"key":"e_1_2_12_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2020.165778"},{"key":"e_1_2_12_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2024.101284"},{"key":"e_1_2_12_147_1","doi-asserted-by":"publisher","DOI":"10.52783\/eel.v12i2.972"},{"key":"e_1_2_12_148_1","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X18666200106155127"},{"key":"e_1_2_12_149_1","doi-asserted-by":"publisher","DOI":"10.3390\/beverages3010006"},{"key":"e_1_2_12_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nutres.2021.08.004"},{"key":"e_1_2_12_151_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201300621"},{"key":"e_1_2_12_152_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10111692"},{"key":"e_1_2_12_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2014.05.017"},{"key":"e_1_2_12_154_1","doi-asserted-by":"publisher","DOI":"10.1007\/7854_2016_12"},{"key":"e_1_2_12_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2014.07.005"},{"key":"e_1_2_12_156_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2021.08.004"},{"key":"e_1_2_12_157_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicines5030076"},{"key":"e_1_2_12_158_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2FO03390A"},{"key":"e_1_2_12_159_1","doi-asserted-by":"publisher","DOI":"10.1097\/JS9.0000000000003030"},{"key":"e_1_2_12_160_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12937\u2010023\u201000859\u20104"},{"key":"e_1_2_12_161_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2012.02.016"},{"key":"e_1_2_12_162_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.pmbts.2015.08.001"},{"key":"e_1_2_12_163_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2011.07.093"},{"key":"e_1_2_12_164_1","doi-asserted-by":"publisher","DOI":"10.1158\/1940\u20106207.CAPR\u201019\u20100383"},{"key":"e_1_2_12_165_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11101\u2010016\u20109459\u2010z"},{"key":"e_1_2_12_166_1","doi-asserted-by":"publisher","DOI":"10.33549\/physiolres.934371"},{"key":"e_1_2_12_167_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2015.09.005"},{"key":"e_1_2_12_168_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11011\u2010021\u201000694\u20108"},{"key":"e_1_2_12_169_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2025.1615883"},{"key":"e_1_2_12_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2022.109094"},{"key":"e_1_2_12_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2020.101696"},{"key":"e_1_2_12_172_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21101305"},{"key":"e_1_2_12_173_1","doi-asserted-by":"publisher","DOI":"10.2183\/pjab.88.88"},{"key":"e_1_2_12_174_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.7033"},{"key":"e_1_2_12_175_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20246196"},{"key":"e_1_2_12_176_1","doi-asserted-by":"publisher","DOI":"10.54254\/2753\u20108818\/15\/20240380"},{"key":"e_1_2_12_177_1","doi-asserted-by":"publisher","DOI":"10.1002\/mdr2.70029"},{"key":"e_1_2_12_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(25)00184\u20109"},{"key":"e_1_2_12_179_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.957516"},{"key":"e_1_2_12_180_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz350"},{"key":"e_1_2_12_181_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.13413"},{"key":"e_1_2_12_182_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.026609"},{"key":"e_1_2_12_183_1","doi-asserted-by":"publisher","DOI":"10.2174\/187152907780830905"},{"key":"e_1_2_12_184_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.49775"},{"key":"e_1_2_12_185_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fshw.2021.12.008"},{"key":"e_1_2_12_186_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2024.1424926"},{"key":"e_1_2_12_187_1","doi-asserted-by":"publisher","DOI":"10.14336\/AD.2018.0513"},{"key":"e_1_2_12_188_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu10101468"},{"key":"e_1_2_12_189_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.28989"},{"key":"e_1_2_12_190_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu12010100"},{"key":"e_1_2_12_191_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD\u2010140981"},{"key":"e_1_2_12_192_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3FO04459A"},{"key":"e_1_2_12_193_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/4532482"},{"key":"e_1_2_12_194_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2019.09.035"},{"key":"e_1_2_12_195_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.3c04524"},{"key":"e_1_2_12_196_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201600305"},{"key":"e_1_2_12_197_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018\u2010017\u20102550\u20109"},{"key":"e_1_2_12_198_1","doi-asserted-by":"publisher","DOI":"10.3390\/beverages2020013"},{"key":"e_1_2_12_199_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43657\u2010024\u201000209\u20102"},{"key":"e_1_2_12_200_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph17060775"},{"key":"e_1_2_12_201_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168\u2010021\u201001115\u20109"},{"key":"e_1_2_12_202_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.951415"},{"key":"e_1_2_12_203_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.200.Supp.53.16"},{"key":"e_1_2_12_204_1","first-page":"45","volume-title":"International Review of Neurobiology","author":"Xu X.","year":"2019"},{"key":"e_1_2_12_205_1","doi-asserted-by":"publisher","DOI":"10.62051\/qv11as62"},{"key":"e_1_2_12_206_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2021.1992748"},{"key":"e_1_2_12_207_1","doi-asserted-by":"publisher","DOI":"10.1155\/ppar\/7178801"},{"key":"e_1_2_12_208_1","doi-asserted-by":"publisher","DOI":"10.38124\/ijisrt\/IJISRT24MAY1166"},{"key":"e_1_2_12_209_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.202000187"},{"key":"e_1_2_12_210_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox9050379"},{"key":"e_1_2_12_211_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43657\u2010024\u201000161\u20101"},{"key":"e_1_2_12_212_1","doi-asserted-by":"publisher","DOI":"10.34133\/2022\/9804014"},{"key":"e_1_2_12_213_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.602748"},{"key":"e_1_2_12_214_1","doi-asserted-by":"publisher","DOI":"10.14283\/jpad.2024.22"},{"key":"e_1_2_12_215_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.105082"},{"key":"e_1_2_12_216_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2022.111762"},{"key":"e_1_2_12_217_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973\u20101296.182174"},{"key":"e_1_2_12_218_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12986\u2010025\u201001047\u20103"},{"key":"e_1_2_12_219_1","doi-asserted-by":"publisher","DOI":"10.1002\/med4.35"},{"key":"e_1_2_12_220_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smhs.2024.02.005"},{"key":"e_1_2_12_221_1","doi-asserted-by":"publisher","DOI":"10.1002\/fft2.465"},{"key":"e_1_2_12_222_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0FO01500H"},{"key":"e_1_2_12_223_1","doi-asserted-by":"publisher","DOI":"10.1159\/000543784"}],"container-title":["Food Science &amp; Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/fsn3.72015","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/fsn3.72015","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/fsn3.72015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T20:31:05Z","timestamp":1787603465000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/fsn3.72015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":222,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/fsn3.72015"],"URL":"https:\/\/doi.org\/10.1002\/fsn3.72015","archive":["Portico"],"relation":{},"ISSN":["2048-7177","2048-7177"],"issn-type":[{"value":"2048-7177","type":"print"},{"value":"2048-7177","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"2025-11-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e72015"}}