{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:01:52Z","timestamp":1790172112359,"version":"4.1.0"},"reference-count":84,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004410","name":"T\u00fcrkiye Bilimsel ve Teknolojik Ara\u015ft\u0131rma Kurumu","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004410","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study comprehensively evaluated the phytochemical composition, biological activities, and biosafety profile of different organs and processing by\u2010products of\n                    <jats:italic>Rosa damascena<\/jats:italic>\n                    , with particular emphasis on valorizing pruning residues and distillation wastes. Extraction yields varied among plant parts, with leaves (29.69%) and flowers (14.15%) providing higher recoveries than buds (7.98%) and branches (7.91%). FTIR\u2010ATR spectroscopy differentiated lignocellulosic woody tissues from phenolic\u2010 and ester\u2010rich floral materials and confirmed the characteristic aliphatic profile of rose oil. Biological activity assays demonstrated strong\n                    <jats:italic>\u03b1<\/jats:italic>\n                    \u2010glucosidase inhibition, particularly in flower extracts (IC\n                    <jats:sub>50<\/jats:sub>\n                    : 37\u2009\u03bcg\/mL), surpassing acarbose, while branches, buds, and leaves also exhibited high activity; in contrast, hydrosol and essential oil showed no measurable inhibition. Antioxidant capacity assays revealed notable radical scavenging and reducing activities, especially in buds, branches, and flowers, whereas hydrosol and essential oil displayed limited effects. Moderate antimicrobial activity was observed mainly against\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    <\/jats:styled-content>\n                    and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Candida albicans<\/jats:italic>\n                    <\/jats:styled-content>\n                    (MIC: 625\u2009\u03bcg\/mL). LC\u2013MS\/MS analysis identified 20 phenolic compounds, with quinic acid as the predominant constituent in buds and flowers. In addition, significant levels of gallic and ellagic acids were detected in distillation wastewater, highlighting the bioactive potential of processing residues. Ames\/\n                    <jats:italic>\n                      Salmonella,\n                      <jats:styled-content style=\"fixed-case\">E. coli<\/jats:styled-content>\n                    <\/jats:italic>\n                    WP2, and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Allium cepa<\/jats:italic>\n                    <\/jats:styled-content>\n                    assays confirmed the absence of genotoxic effects at tested concentrations. Overall, the findings demonstrate that\n                    <jats:italic>R. damascena<\/jats:italic>\n                    organs and industrial by\u2010products represent valuable sources of bioactive compounds, exhibiting in\u00a0vitro\n                    <jats:italic>\u03b1<\/jats:italic>\n                    \u2010glucosidase and\n                    <jats:italic>\u03b1<\/jats:italic>\n                    \u2010amylase inhibitory activities associated with potential antidiabetic effects, as well as notable antioxidant capacity, thereby supporting their prospective utilization in functional food and nutraceutical applications.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.72072","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T07:40:36Z","timestamp":1782978036000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comprehensive Chemical and Biological Evaluation of\n                    <i>Rosa damascena<\/i>\n                    Plant Parts and Industrial Residues Using FTIR\u2010ATR and LC\u2013MS\/MS"],"prefix":"10.1002","volume":"14","author":[{"given":"Burak","family":"Bayrak","sequence":"first","affiliation":[{"name":"Department of Analytical Chemistry, Faculty of Pharmacy Ataturk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0857-4776","authenticated-orcid":false,"given":"Hafize","family":"Yuca","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Faculty of Pharmacy Ataturk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasemin Beyza","family":"Budak","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Faculty of Pharmacy Ataturk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satuk Bu\u011fra","family":"Alkuyruk","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Microbiology, Faculty of Pharmacy Ataturk University  Erzurum T\u00fcrkiye"},{"name":"Graduate School of Health Sciences Ankara University  Ankara T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elif Beyza","family":"\u00d6zer","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Faculty of Pharmacy Ataturk University  Erzurum T\u00fcrkiye"},{"name":"Department of Pharmacognosy, Faculty of Pharmacy Ondokuz May\u0131s University  Samsun T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6869-8703","authenticated-orcid":false,"given":"G\u00fclnur Ek\u015fi","family":"Bona","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Botany, Faculty of Pharmacy Istanbul University\u2010Cerrahpa\u015fa  \u0130stanbul T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilge","family":"Ayd\u0131n","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Faculty of Pharmacy Erzincan Binali Y\u0131ld\u0131r\u0131m University  Erzincan T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Karaday\u0131","sequence":"additional","affiliation":[{"name":"Department of Biology, Faculty of Science Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuf","family":"G\u00fcl\u015fahin","sequence":"additional","affiliation":[{"name":"Department of Biology, Faculty of Science Atat\u00fcrk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alptu\u011f","family":"Atila","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Faculty of Pharmacy Ataturk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamze","family":"G\u00f6ger","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Faculty of Pharmacy Afyokarahisar Health Sciences University  Afyon T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3268-721X","authenticated-orcid":false,"given":"Songul","family":"Karakaya","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Botany, Faculty of Pharmacy Ataturk University  Erzurum T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,2]]},"reference":[{"issue":"2017","key":"e_1_2_13_2_1","first-page":"12","article-title":"Phytochemical Analysis of \n                     Quercus infectoria\n                   Galls Extracts Using FTIR, LC\u2010MS and MS\/MS Analysis","volume":"12","author":"Abdullah A. 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