{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:02:35Z","timestamp":1790172155179,"version":"4.1.0"},"reference-count":95,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Salvia<\/jats:italic>\n                    (Lamiaceae) species have been used in food, cosmetics, and medicine for centuries. Besides their use as food, these species are potential raw material candidates for pharmaceuticals due to their rich phytochemical content. Studies on the endemic Turkish\n                    <jats:italic>Salvia<\/jats:italic>\n                    species examined in this study,\n                    <jats:italic>S.\u2009ballsiana<\/jats:italic>\n                    (Rech.f.) Hedge,\n                    <jats:italic>S.\u2009hedgeana<\/jats:italic>\n                    D\u00f6nmez, and\n                    <jats:italic>S.\u2009vermifolia<\/jats:italic>\n                    Hedge &amp; Hub.\u2010Mor., are very limited. The aim of this study is to evaluate the antioxidant, antidiabetic, and anti\u2010obesity effects of these species and to elucidate their chemical profiles. In this context, the antidiabetic effect was determined by \u03b1\u2010glucosidase and \u03b1\u2010amylase inhibitory activity tests, and the anti\u2010obesity effect was determined by the pancreatic lipase inhibitory activity test. The chemical profiles of the extracts were determined by LC\u2013MS\/MS.\n                    <jats:italic>S.\u2009vermifolia<\/jats:italic>\n                    and\n                    <jats:italic>S.\u2009hedgeana<\/jats:italic>\n                    demonstrated strong \u03b1\u2010glucosidase inhibitory activity (IC\n                    <jats:sub>50<\/jats:sub>\n                    values of 36.46\u2009\u00b1\u20091.25 and 52.89\u2009\u00b1\u20093.36\u2009\u03bcg\/mL, respectively). Among the extracts, the strongest \u03b1\u2010amylase and pancreatic lipase inhibitory activity was found in the\n                    <jats:italic>S.\u2009vermifolia<\/jats:italic>\n                    extract (IC\n                    <jats:sub>50<\/jats:sub>\n                    values 68.38\u2009\u00b1\u20094.27 and 89.46\u2009\u00b1\u20096.80\u2009\u03bcg\/mL, respectively). Additionally, the reference compounds acarbose and orlistat exhibited stronger inhibitory activity than all extracts: acarbose showed IC\n                    <jats:sub>50<\/jats:sub>\n                    values of 1.52\u2009\u00b1\u20090.15 and 2.99\u2009\u00b1\u20090.04\u2009\u03bcg\/mL for \u03b1\u2010glucosidase and \u03b1\u2010amylase, respectively, while orlistat demonstrated pancreatic lipase inhibition with an IC\n                    <jats:sub>50<\/jats:sub>\n                    value of 11.82\u2009\u00b1\u20092.54\u2009\u03bcg\/mL.\n                    <jats:italic>S.\u2009vermifolia<\/jats:italic>\n                    extract demonstrated strong metal chelation capacity, ABTS and DPPH radical scavenging activity (65.50%, 70.73% and 83.80%, respectively). Rosmarinic acid was found to be major phytoconstituent of the species with the highest inhibition potency on enzymes (\n                    <jats:italic>S.\u2009vermifolia<\/jats:italic>\n                    ). Binding potential and mode of action for rosmarinic acid were explored through molecular docking. Results that corroborated the enzymatic assay studies were obtained.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.72149","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T05:02:36Z","timestamp":1784782956000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Phytochemical Profiling and Evaluation of Antioxidant and Enzyme Inhibitory Activities of Selected Endemic\n                    <i>Salvia<\/i>\n                    Species (Lamiaceae) From T\u00fcrkiye"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4098-0221","authenticated-orcid":false,"given":"Semih","family":"Bulut","sequence":"first","affiliation":[{"name":"Department of Pharmacognosy, Faculty of Pharmacy Suleyman Demirel University  Isparta 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