{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T04:53:21Z","timestamp":1791003201550,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005951","name":"Honjo International Scholarship Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005951","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp;amp; Nutrition"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Obesity is a major risk factor for the development of lifestyle\u2010related diseases worldwide. Green tea (GT) and catechins have been reported to ameliorate obesity\u2010related phenotypes, whereas the metabolic effects of Sunrouge (SR), a GT cultivar containing both catechins and anthocyanins, remain insufficiently characterized. In this study, we investigated the effects of long\u2010term SR intake in Western diet (WD)\u2010fed male C57BL\/6J mice and examined the effects of epigallocatechin gallate (EGCG) and delphinidin\u20103\u2010\n                    <jats:italic>O<\/jats:italic>\n                    \u2010galactoside (D3Ga), representative SR polyphenols, in HepG2 cells. In WD\u2010fed mice, both SR and GT attenuated adipose tissue mass, hepatic triglyceride (TG) and nonesterified fatty acid (NEFA) accumulation, and improved glucose tolerance in the intraperitoneal glucose tolerance test. SR additionally reduced plasma and hepatic total cholesterol and increased fasting plasma active glucagon\u2010like peptide\u20101 concentrations. SR also altered cecal organic acid profiles and intestinal microbiota composition. In HepG2 cells, D3Ga significantly reduced NEFA\u2010induced intracellular TG accumulation, and co\u2010treatment with EGCG and D3Ga increased\n                    <jats:italic>CPT1<\/jats:italic>\n                    expression. These findings suggest that SR, like GT, attenuates diet\u2010induced fat accumulation and several obesity\u2010related metabolic abnormalities. SR also affected cholesterol metabolism, fasting plasma active GLP\u20101 levels, and gut microbial profiles, suggesting a partly distinct metabolic profile from GT. This study provides new insights into the potential metabolic benefits of anthocyanin\u2010containing GT cultivars.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.72186","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T10:54:50Z","timestamp":1787741690000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sunrouge, an Anthocyanin\u2010Rich Green Tea Cultivar, Attenuates Fat Accumulation and Obesity\u2010Related Metabolic Abnormalities in Western Diet\u2010Fed Mice"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4160-2418","authenticated-orcid":false,"given":"Chika","family":"Ando","sequence":"first","affiliation":[{"name":"Graduate School of Agricultural and Life Sciences The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0226-1277","authenticated-orcid":false,"given":"Kyohei","family":"Furukawa","sequence":"additional","affiliation":[{"name":"Graduate School of Agricultural and Life Sciences The University of Tokyo  Tokyo Japan"},{"name":"Animal Nutrition, Graduate School of Bioagricultural Sciences Nagoya University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunichi","family":"Someya","sequence":"additional","affiliation":[{"name":"Graduate School of Agricultural and Life Sciences The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongshou","family":"Yang","sequence":"additional","affiliation":[{"name":"Graduate School of Agricultural and Life Sciences The University of Tokyo  Tokyo Japan"},{"name":"School of Life Sciences Anhui University  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3362-3872","authenticated-orcid":false,"given":"Maki","family":"Igarashi","sequence":"additional","affiliation":[{"name":"Graduate School of Agricultural and Life Sciences The University of Tokyo  Tokyo Japan"},{"name":"Division of Epidemiology National Cancer Center Institute for Cancer Control  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seigo","family":"Yamada","sequence":"additional","affiliation":[{"name":"AZUMA CHEMICAL Co. 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