{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T04:52:56Z","timestamp":1791003176585,"version":"4.1.0"},"reference-count":74,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp;amp; Nutrition"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The investigation of the biological activities of plants utilized in traditional medicine to treat various illnesses is of great importance for their potential evaluation as pharmaceutical raw materials in modern medicine. In the present study, the anticancer, antimicrobial, and anti\u2010quorum\u2010sensing (anti\u2010QS) activities of ethyl acetate, ethanol, ethanol\u2010water, and water extracts prepared from the aerial parts of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Eryngium campestre<\/jats:italic>\n                    <\/jats:styled-content>\n                    by maceration were tested. The biological content, antioxidant, and enzyme\u2010inhibitory capacity of the extracts were also investigated.\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>E. campestre<\/jats:italic>\n                    <\/jats:styled-content>\n                    extracts possess a rich flavonoid and phenolic composition. The ethanol\u2010water extract had the highest total polyphenol content. 3\u2010hydroxybenzoic acid, 4\u2010hydroxybenzoic acid, vanillic acid, p\u2010coumaric acid, and ferulic acid were common and abundant across all extracts. The ethanol extract showed the highest enzyme\u2010inhibitory activity in acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) tests with values of 2.68 and 3.17\u2009mg GALAE\/g, respectively. The anticancer activity results revealed that the lowest 50% inhibitory concentration (IC\n                    <jats:sub>50<\/jats:sub>\n                    ) for cell viability in the MDA\u2010MB\u2010231 cell line was 215.2\u2009\u03bcg\/mL for the ethanol extract. For the HeLa cell line, the lowest IC\n                    <jats:sub>50<\/jats:sub>\n                    value was defined as 151.7\u2009\u03bcg\/mL for the ethyl acetate extract. No antimicrobial effects were detected in the tested concentrations of the extracts against reference microbial strains. To determine anti\u2010QS activity, the inhibitory effect on violacein pigment production was investigated on the\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Chromobacterium violaceum<\/jats:italic>\n                    <\/jats:styled-content>\n                    CV026 mutant strain. No inhibition of pigment production was observed in the study. Based on the findings,\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>E. campestre<\/jats:italic>\n                    <\/jats:styled-content>\n                    may have potential for further anticancer research and pharmacological studies.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.72250","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T05:03:28Z","timestamp":1786424608000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Potent Therapeutic Insights From\n                    <i>Eryngium campestre<\/i>\n                    : Phytochemical Profiling and In Vitro Evaluation"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-8803-0296","authenticated-orcid":false,"given":"K\u00fcbra","family":"Seyhan","sequence":"first","affiliation":[{"name":"Plantomics Research Laboratory, 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