{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T04:53:10Z","timestamp":1791003190428,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32572590"],"award-info":[{"award-number":["32572590"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012246","name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp;amp; Nutrition"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Inflammatory bowel disease (IBD) has emerged as a global health concern. This study aimed to evaluate the ameliorative effects of the combined application of rice bran (RB) and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Lactobacillus johnsonii<\/jats:italic>\n                    <\/jats:styled-content>\n                    23, a producer of feruloyl esterase, on dextran sulfate sodium (DSS)\u2010induced ulcerative colitis (UC) in mice. High\u2010yielding ferulic acid esterase bacteria (FAEb) were screened and administered to DSS\u2010induced UC mice along with rice bran. Disease symptoms, histopathology, oxidative stress, inflammatory factors, and cecal short\u2010chain fatty acids (SCFAs) were assessed to evaluate the alleviating effects on UC mice. The combined intervention effectively improved body weight changes, disease activity index (DAI) scores, and colon length in UC mice, reversing DSS\u2010induced epithelial cell necrosis, crypt structural loss, inflammatory cell infiltration, goblet cell depletion, and mucosal erosion and edema. The combination also reduced colonic MDA levels, enhanced SOD, GSH, and GSH\u2010Px levels, thereby boosting antioxidant capacity. It decreased the expression of proinflammatory cytokines IL\u20106, IL\u20101\u03b2, and TNF\u2010\u03b1 while increasing the expression of the anti\u2010inflammatory factor IL\u201010, promoting anti\u2010inflammatory capacity. Furthermore, the combined application resisted DSS\u2010induced depletion of SCFAs. The combined administration of rice bran and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>L. johnsonii<\/jats:italic>\n                    <\/jats:styled-content>\n                    23 holds the potential to emerge as a novel dietary supplement for the prevention or treatment of UC.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.72261","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T04:38:39Z","timestamp":1787373519000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Combined Administration of Rice Bran and Bacteria Producing Feruloyl Esterase Alleviates\n                    <scp>DSS<\/scp>\n                    \u2010Induced Ulcerative Colitis in Mice"],"prefix":"10.1002","volume":"14","author":[{"given":"Le","family":"Li","sequence":"first","affiliation":[{"name":"College of Food Science and Engineering Nanjing University of Finance and Economics\/Collaborative Innovation Center for Modern Grain Circulation and Safety  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feiyu","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering Nanjing University of Finance and Economics\/Collaborative Innovation Center for Modern Grain Circulation and Safety  Nanjing China"},{"name":"College of Food Science and Technology Nanjing Agricultural University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8655-0166","authenticated-orcid":false,"given":"Dan","family":"Shen","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering Nanjing University of Finance and Economics\/Collaborative Innovation Center for Modern Grain Circulation and Safety  Nanjing 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