{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:59:12Z","timestamp":1790405952687,"version":"4.1.0"},"reference-count":93,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp;amp; Nutrition"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Nanoparticles have attracted considerable attention due to their high surface area\u2010to\u2010volume ratio, tunable size, unique physicochemical properties, and, depending on their composition, favorable electrical, photocatalytic, and biocompatible characteristics. Silver nanoparticles (AgNPs) were prepared using a green synthesis approach employing the leaf extracts of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Cydonia oblonga<\/jats:italic>\n                    <\/jats:styled-content>\n                    ,\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Actinidia deliciosa<\/jats:italic>\n                    <\/jats:styled-content>\n                    ,\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Prunus spinosa<\/jats:italic>\n                    <\/jats:styled-content>\n                    , and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Prunus laurocerasus<\/jats:italic>\n                    <\/jats:styled-content>\n                    . The synthesized AgNPs were characterized using UV\u2010Vis spectroscopy, FTIR, and SEM\u2010EDX. Furthermore, the potential antioxidant, anti\u2010inflammatory, antibacterial, and GST inhibitory activities of these AgNPs were assessed. Among all prepared nanomaterials, AgNPs produced using\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>C.\u2009oblonga<\/jats:italic>\n                    <\/jats:styled-content>\n                    leaf extract (AgNP\u20101) displayed the highest antioxidant capacity (IC\n                    <jats:sub>50<\/jats:sub>\n                    \u2009=\u20094.14\u2009\u00b1\u20090.04\u2009\u03bcg\/mL) and outstanding anti\u2010inflammatory effects (98.48%). Additionally, AgNP\u20101 showed the strongest GST inhibition activity (IC50\u2009=\u20091.306\u2009\u00b1\u20090.12\u2009mg\/mL). Conversely, AgNPs produced using\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>P.\u2009laurocerasus<\/jats:italic>\n                    <\/jats:styled-content>\n                    leaf extract (AgNP\u20104) exhibited the strongest antibacterial activity, displaying MIC values ranging from 39 to 78\u2009\u03bcg\/mL against different bacterial species, and the greatest GST inhibitory activity (IC\n                    <jats:sub>50<\/jats:sub>\n                    \u2009=\u20090.965\u2009\u00b1\u20090.02\u2009mg\/mL). Moreover, molecular docking studies showed that the phenolic hydroxyl functional groups of the metabolites found in the plant extracts exhibited strong interaction with the GST active site through conventional hydrogen bond formation, electrostatic interactions, hydrophobic interactions, and metal acceptor interactions, whereas AgNPs interacted with GST primarily through metal acceptor interactions. Therefore, the current study revealed that plant\u2010mediated, biologically synthesized AgNPs exhibit promising biomedical properties and may serve as potential candidates for the development of antimicrobial agents, anti\u2010inflammatory agents, antioxidants, and enzyme inhibitors because of their significant antibacterial, anti\u2010inflammatory, antioxidant, and GST\u2010inhibitory effects.\n                  <\/jats:p>","DOI":"10.1002\/fsn3.72288","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T07:14:02Z","timestamp":1789456442000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Green Synthesis of Silver Nanoparticles From Various Leaves Extract: Antioxidant, Anti\u2010Inflammatory, Antibacterial Activities and Inhibitory Effect on Glutathione 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