{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T16:27:16Z","timestamp":1790958436082,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T00:00:00Z","timestamp":1550620800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20141255"],"award-info":[{"award-number":["BK20141255"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Food Science &amp; Nutrition"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In east Asia, \u201cBaishouwu\u201d has been used as an herbal drug and functional dietary supplement for hundreds of years. Actually, \u201cBaishouwu\u201d is the common name of the roots of <jats:italic>Cynanchum auriculatum<\/jats:italic>,<jats:italic> Cynanchum bungei<\/jats:italic>, and <jats:italic>Cynanchum wilfordii<\/jats:italic>. In the present study, roots of these three specie were extracted and then fractionated using petroleum ether (PE), dichloromethane (DCM), ethyl acetate (EA), and water. DPPH scavenging experiments revealed high antioxidant activity of DCM and EA fractions of <jats:italic>C.\u00a0bungei<\/jats:italic> and the EA fraction of <jats:italic>C.\u00a0wilfordii<\/jats:italic>. Treatments with these three fractions significantly reduced malondialdehyde content in heat\u2010stressed <jats:italic>Daphnia magna<\/jats:italic>, validating in vivo antioxidant activity. Gas chromatography\u2013mass spectrometer (GC\u2010MS) analyses demonstrated that the chemical components of fractions extracted from <jats:italic>C.\u00a0bungei<\/jats:italic>,<jats:italic> C.\u00a0bungei<\/jats:italic>, and <jats:italic>C.\u00a0wilfordii<\/jats:italic> were different. Further determination of total phenol and total flavonoids contents showed that DCM and EA fractions of <jats:italic>C.\u00a0bungei<\/jats:italic> and EA fraction of <jats:italic>C.\u00a0wilfordii<\/jats:italic> had much higher contents of total phenol and total flavonoids, which might be the reason to explain their strong antioxidant activity. Overall, the present study suggested that these three plants have different chemical components and biological activities. They could not be used as the same drug.<\/jats:p>","DOI":"10.1002\/fsn3.967","type":"journal-article","created":{"date-parts":[[2019,2,21]],"date-time":"2019-02-21T06:44:09Z","timestamp":1550731449000},"page":"1337-1343","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Selection of solvent for extraction of antioxidant components from <i>Cynanchum auriculatum<\/i>,<i> Cynanchum bungei<\/i>, and <i>Cynanchum wilfordii<\/i> roots"],"prefix":"10.1002","volume":"7","author":[{"given":"Cheng\u2010Dong","family":"Wu","sequence":"first","affiliation":[{"name":"Xinyang Agricultural Experiment Station of Yancheng City Yancheng China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Zhang","sequence":"additional","affiliation":[{"name":"Xinyang Agricultural Experiment Station of Yancheng City Yancheng China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming\u2010Tao","family":"He","sequence":"additional","affiliation":[{"name":"Xinyang Agricultural Experiment Station of Yancheng City Yancheng China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min\u2010Feng","family":"Gu","sequence":"additional","affiliation":[{"name":"Xinyang Agricultural Experiment Station of Yancheng City Yancheng China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Lin","sequence":"additional","affiliation":[{"name":"Shenzhen GenProMetab Biotechnology Company Limited Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8619-3285","authenticated-orcid":false,"given":"Gen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shenzhen GenProMetab Biotechnology Company Limited Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/pm.pm_212_17"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1042\/BC20100145"},{"key":"e_1_2_7_4_1","first-page":"93","article-title":"Protective effects of radix Cynanchum bungei on ischemia\u2010induced neuronal and cognitive impairment in mice","volume":"31","author":"Chen M.\u2010H.","year":"2017","journal-title":"Chinese Journal of Pharmacology and Toxicology"},{"key":"e_1_2_7_5_1","first-page":"35","article-title":"Acetophenones and antioxidant activity in Cynanchum auriculatum Royle ex Wight","volume":"5","author":"Chen B.\u2010Y.","year":"2013","journal-title":"Journal of Pharmaceutical Practice"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/ie50359a024"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2011.01302.x"},{"key":"e_1_2_7_8_1","first-page":"237","article-title":"Determination of SOD specific activity in animal and plant tissues by improved xanthine oxidase method","volume":"32","author":"Dong X. 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