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This is the first case report of a primary renal spindle cell neoplasm of uncertain malignant potential with a <jats:italic>HEY1::NCOA2<\/jats:italic> fusion identified by Fusionplex RNA\u2010sequencing that is histologically distinct from mesenchymal chondrosarcoma. The neoplasm was identified in a 33\u2010year\u2010old woman without significant past medical history who underwent partial nephrectomy for an incidentally discovered renal mass. The histologic features of the mass included spindle cells with variable cellularity and monotonous bland cytology forming vague fascicles and storiform architecture within a myxoedematous and collagenous stroma with areas of calcification. The morphologic and immunophenotypic features were not specific for any entity but were most similar to low\u2010grade fibromyxoid sarcoma. 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