{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:31:00Z","timestamp":1790173860889,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,14]],"date-time":"2006-07-14T00:00:00Z","timestamp":1152835200000},"content-version":"vor","delay-in-days":5064,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genes Chromosomes &amp; Cancer"],"published-print":{"date-parts":[[1992,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The translocation t( 11; I4)(q 13;q32) has been described in a spectrum of B\u2010lymphoproliferative diseases and involves a putative oncogene, <jats:italic>BCLI<\/jats:italic>, which maps to chromosome band 11q13. Recent evidence indicates that this abnormality may delineate particular subtypes of lymphoma, such as intermediate lymphocytic and centrocytic lymphomas. Thus the possible significance of the t(111;14) within B\u2010cell disorders should be reexamined in the light of a more objective approach to classifying these diseases by morphology, histology, and immunophenotype. We describe 16 patients with t(11;14)(q13;q32) from a series of 90 patients with chronic lymphoid disorders in whom clonal chromosome abnormalities were detected. All the cases were leukemic: prolymphocytic (B\u2010PLL; <jats:sup>4<\/jats:sup>\/<jats:sub>15<\/jats:sub> cases), chronic lymphocytic leukemia (CLL) with increase in prolymphocytes (<jats:sup>2<\/jats:sup>\/<jats:sub>9<\/jats:sub> cases), or non\u2010Hodgkin lymphoma in leukemic phase, intermediate (<jats:sup>3<\/jats:sup>\/<jats:sub>4<\/jats:sub> cases), lymphoplasmacytic (<jats:sup>2<\/jats:sup>\/<jats:sub>2<\/jats:sub> cases), splenic lymphoma with villous lymphocytes (<jats:sup>4<\/jats:sup>\/<jats:sub>18<\/jats:sub> cases), and follicular (I case). None of the CLL (25) or hairy cell leukemia cases (15) had t(11;14). Our findings showed that t(11;14) occurred in leukemias of mature B cells with lymphoplasmacytic features as judged by morphology and immunophenotype.<\/jats:p>","DOI":"10.1002\/gcc.2870050210","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T23:09:33Z","timestamp":1172099373000},"page":"158-165","source":"Crossref","is-referenced-by-count":61,"title":["Translocation t(11; 14)(q 13;q32) in chronic lymphoid disorders"],"prefix":"10.1002","volume":"5","author":[{"given":"V.","family":"Brito\u2010Babapulie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Ellis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Matutes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Oscier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Khokhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"MacLennan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Catovsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,14]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"591","article-title":"BCL\u20101 gene rearrangement: Frequency and clinical significance among B\u2010cell chronic lymphocytic leukemias and non\u2010Hodgkin's lymphomas","volume":"138","author":"Athan E","year":"1991","journal-title":"Am J Pathol"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.42.6.567"},{"key":"e_1_2_1_4_1","first-page":"27","article-title":"Cytogenetic studies on prolymphocytic leukemia. 1. 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