{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T02:54:22Z","timestamp":1780628062144,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,7,14]],"date-time":"2006-07-14T00:00:00Z","timestamp":1152835200000},"content-version":"vor","delay-in-days":5034,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genes Chromosomes &amp; Cancer"],"published-print":{"date-parts":[[1992,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Many nonrandom chromosome abnormalities have been associated with non\u2010Hodgkin's lymphomas (NHL). Some of these are nonspecific changes seen in many different histologic subtypes. We describe a series of abnormalities of chromosome bands 10q23\u201325 seen in 159 consecutive NHL patients with abnormal cytogenetic findings. The proportion of karyotypes with abnormalities of 10q varied from 3% among the immunoblastic lymphomas to 67% in the diffuse large cleaved cell lymphomas. Seventeen (10.7%) had abnormalities of 10q23\u201325. All but one of these were B\u2010cell tumors. The abnormalities consisted of six deletions and 11 translocations. Sixteen of the 17 patients had the 10q abnormality when cells were first karyotyped. The remaining patient acquired the 10q abnormality in the third of a series of biopsies. In the follicular histologic subtypes [follicular small cleaved cell (FSC), follicular mixed small cleaved and large cell (FM), and follicular large cell noncleaved (FL\u2010NC)], abnormalities of 10q were found in nine patients, all in association with abnormalities of 14q32. Seven of these were associated with the t(14;18)(q32;q21). Overall, 10q23\u201325 abnormalities were observed in 11.9% (8\/67) of low\u2010grade [small lymphocytic (SL), FSC, and FM] lymphoma cases. DNA was available from five patients with abnormalities of 10q and was probed for rearrangements with the <jats:italic>HOX11 (TCL3)<\/jats:italic> oncogene probe. As expected, we did not find such rearrangements in these five patients with B\u2010cell tumors. Abnormalities of 10q23\u201325 have been reported previously in NHL but not at this frequency.<\/jats:p>","DOI":"10.1002\/gcc.2870050311","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T23:09:24Z","timestamp":1172099364000},"page":"239-243","source":"Crossref","is-referenced-by-count":40,"title":["Recurrent abnormalities of chromosome bands 10q23\u201325 in non\u2010Hodgkin's lymphoma"],"prefix":"10.1002","volume":"5","author":[{"given":"Susan L.","family":"Speaks","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren G.","family":"Sanger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aneal S.","family":"Masih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas S.","family":"Harrington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Hess","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James O.","family":"Armitage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,14]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/80.8.576"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00295378"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","unstructured":"BabuVR MilesBJ CerneyJC CrissmanJD DrumhellerT WeissL VanDykeDL(1989)A prospective study of 92 bladder cancer patients: Cytogenetics histopathology and tumor behavior. Paper presented at the Third International Workshop on Chromosomes in Solid Tumors Arizona Cancer Center University of Arizona February 26\u2010March 1 1989.","DOI":"10.1016\/0165-4608(89)90275-6"},{"key":"e_1_2_1_5_1","first-page":"405","article-title":"Specific chromosomal abnormalities in malignant human gliomas","volume":"88","author":"Bigner SH","year":"1988","journal-title":"Cancer Res"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1182\/blood.V67.4.1181.1181","article-title":"A new translocation, t(10; 14)(q24;q11), in T\u2010cell neoplasia","volume":"67","author":"Dub\u00e9 ID","year":"1986","journal-title":"Blood"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0888-7543(89)90302-9"},{"key":"e_1_2_1_8_1","first-page":"3119","article-title":"Chromosome abnormalities in poorly differentiated lymphocytic lymphoma","volume":"39","author":"Fukuhara S","year":"1979","journal-title":"Cancer Res"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hon.2900020406"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1676542"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6438800"},{"key":"e_1_2_1_12_1","volume-title":"Published in collaboration with Cytogenet Cell Genet","author":"ISCN","year":"1985"},{"key":"e_1_2_1_12_2","unstructured":"(Also in Birth Defects: Original Articles Series Vol. 21 No. 1. New York: March of Dimes Birth Defects Foundation 1985)."},{"key":"e_1_2_1_13_1","first-page":"5546","article-title":"Clonal genomic alterations in glioma malignancy stages","volume":"48","author":"James CD","year":"1988","journal-title":"Cancer Res"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1990.tb07877.x"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.13.4543"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.11.4161"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.20.8900"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1991.tb07840.x"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/237033a0"},{"key":"e_1_2_1_20_1","volume-title":"Catalog of Chromosome Aberrations in Cancer","author":"Mitelman F","year":"1988"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90285-7"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.2870030304"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V77.7.1508.1508"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-4608(88)90200-2"},{"key":"e_1_2_1_25_1","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1182\/blood.V70.5.1554.1554","article-title":"Fifth International Workshop on Chromosomes in Leukemia\u2010Lymphoma. Correlation of chromosome abnormalities with histologic and immunologic characteristics in non\u2010Hodgkin's lymphoma and adult T\u2010cell leukemia\u2010lymphoma","volume":"70","author":"Sakurai M","year":"1987","journal-title":"Blood"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00285178"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00291730"},{"key":"e_1_2_1_28_1","doi-asserted-by":"crossref","unstructured":"SreekantaishC Krishna BhargavaM ShettyNJ SandbergAA(1989) Deletion (10)(q24):A nonrandom change in cancer of the uterine cervix. 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