{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:47:21Z","timestamp":1761518841162},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,14]],"date-time":"2006-07-14T00:00:00Z","timestamp":1152835200000},"content-version":"vor","delay-in-days":4822,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genes Chromosomes & Cancer"],"published-print":{"date-parts":[[1993,5]]},"abstract":"Abstract<\/jats:title>We describe a patient with stage IV non\u2010Hodgkin's lymphoma (NHL) and a t(11;18)(q21;q21) translocation. He presented with a gastric small B\u2010cell lymphocytic lymphoma, expressing IgAL immunoglobulins without expression of CD10, CD5, and CD23 antigens. The lymphoma was the final development of a 6\u2010year history of a monoclonal IgAL increase complicated by severe renal failure due to membranoproliferative glomerulonephritis. The clinical, histological, immunologic, and cytogenetic features of this patient are very similar to those observed in the five other patients with t(11;18) reported to date. This translocation therefore seems to delineate a new subtype of diffuse small B\u2010cell lymphoma with involvement of mucosal sites. Involvement of the BCL2<\/jats:italic> oncogene on 18q21 could not be detected using molecular techniques with 5\u2032 as well as 3\u2032 BCL2<\/jats:italic> probes, indicating that other, so far unknown, genes relevant to lymphoid differentiation could be located in 18q21 and 11q21. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/gcc.2870070109","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T23:42:19Z","timestamp":1172101339000},"page":"54-56","source":"Crossref","is-referenced-by-count":30,"title":["t(11;18)(q21;q21) may delineate a spectrum of diffuse small B\u2010cell lymphoma with extranodal involvement"],"prefix":"10.1002","volume":"7","author":[{"given":"Dominique","family":"Leroux","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paule","family":"Seit\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josette","family":"Hillion","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"le Marc'hadour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brigitte","family":"P\u00e9gouri\u00e9\u2010Bandelier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie\u2010Christine","family":"Jacob","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian\u2010Jacques","family":"Larsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Jacques","family":"Sotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,14]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.171.2.559"},{"key":"e_1_2_1_3_1","first-page":"560","article-title":"Chromosomal rearrangement on chromosome 11q14\u2013q21 in T\u2010cell acute lymphoblastic leukemia","volume":"3","author":"Berger R","year":"1989","journal-title":"Leukemia"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3538420"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.2870040209"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.2870040213"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1990.tb01173.x"},{"key":"e_1_2_1_8_1","volume-title":"Guidelines for Cancer Cytogenetics, Supplement to An International System for Human Cytogenetic Nomenclature","author":"ISCN","year":"1991"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V69.1.97.97"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1991.tb08582.x"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1182\/blood.V74.5.1796.1796","article-title":"Four new recurring translocations in non\u2010Hodgkin's lymphoma","volume":"74","author":"Levine EG","year":"1989","journal-title":"Blood"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1985.tb04100.x"},{"key":"e_1_2_1_13_1","doi-asserted-by":"crossref","unstructured":"RimokhR GadouxM Berth\u00e9asMF BergerF GaroscioM Del\u00e9ageG GermainD MagaudJP(1992) FVT\u20101 a novel human transcription unit affected by variant translocation t(2;18)(p11;q21) of follicular lymphoma. Blood in press.","DOI":"10.1182\/blood.V81.1.136.136"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","unstructured":"Seit\u00e9P LerouxD HillionJ BergerR Mathieu\u2010MahulD LarsenCJ(1992) Molecular analysis of a variant t(18;22) in a lymphocytic lymphoma.Genes Chrom Cancer in press.","DOI":"10.1002\/gcc.2870060108"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1988.tb02791.x"}],"container-title":["Genes, Chromosomes and Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fgcc.2870070109","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/gcc.2870070109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T20:28:44Z","timestamp":1698179324000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/gcc.2870070109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,5]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1993,5]]}},"alternative-id":["10.1002\/gcc.2870070109"],"URL":"https:\/\/doi.org\/10.1002\/gcc.2870070109","archive":["Portico"],"relation":{},"ISSN":["1045-2257","1098-2264"],"issn-type":[{"value":"1045-2257","type":"print"},{"value":"1098-2264","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,5]]}}}