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The other had a non\u2010osseous tumor with an interstitial deletion, del(18)(q12.2q21.2), was resistant to combination therapy, and at autopsy had evidence of possible clonal evolution with the karyotype 46,XX der(8)t (8;8)(p11.2;q13), inv(16)(p13.2q12), del(18)(q12.2q21.2). Neither tumor demonstrated the t(11;22)(q24;q12) typically found in Ewing's sarcoma and PPNET, suggesting heterogeneity of the cytogenetic aberrations seen in this rare childhood malignancy.<\/jats:p>","DOI":"10.1002\/gcc.2870120209","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T00:14:03Z","timestamp":1172103243000},"page":"142-147","source":"Crossref","is-referenced-by-count":2,"title":["Atypical cytogenetic aberrations in two childhood peripheral primitive neuroectodermal Tumors"],"prefix":"10.1002","volume":"12","author":[{"given":"Jeffrey C.","family":"Murray","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Langston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoann E.","family":"Dreyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles 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