{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T23:17:16Z","timestamp":1773962236988,"version":"3.50.1"},"reference-count":8,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Genes Chromosomes &amp;amp; Cancer"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The increasing application of molecular diagnostics in pathology has enabled the identification of novel tumor entities, including clear cell tumor with\n                    <jats:italic>MITF::CREM<\/jats:italic>\n                    translocation, as recognized in the 5th edition of the WHO Classification of Tumours. We describe a case involving a 2\u2010year\u2010old boy with a left scalp lesion, initially suspected clinically to represent a pyogenic granuloma. Histopathological assessment, corroborated by molecular analysis, established the diagnosis of clear cell tumor with\n                    <jats:italic>MITF::CREM<\/jats:italic>\n                    translocation. This case emphasizes the need to consider rare entities in the differential diagnosis of dermal lesions and highlights the critical role of molecular testing in diagnostic precision. Notably, this molecularly defined neoplasm demonstrated no immunohistochemical evidence of melanocytic differentiation, contrasting with the features described in the WHO classification.\n                  <\/jats:p>","DOI":"10.1002\/gcc.70099","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T10:34:10Z","timestamp":1768991650000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clear Cell Tumor With\n                    <i>MITF::CREM<\/i>\n                    Fusion: A Rare Case Report of a Newly Described Entity"],"prefix":"10.1002","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4012-1942","authenticated-orcid":false,"given":"Michael","family":"Lie","sequence":"first","affiliation":[{"name":"Department of Anatomical Pathology Women's and Children's Hospital, SA Pathology  North Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7755-8745","authenticated-orcid":false,"given":"Pranav","family":"Dorwal","sequence":"additional","affiliation":[{"name":"Department of Pathology Monash Health  Clayton Victoria Australia"},{"name":"Department of Medicine, School of Clinical Sciences Monash University  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5245-3080","authenticated-orcid":false,"given":"Liyan","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Pathology Monash Health  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aditya","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Women's and Children's Hospital  North Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0487-3197","authenticated-orcid":false,"given":"Lynette","family":"Moore","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology Women's and Children's Hospital, SA Pathology  North Adelaide South Australia Australia"},{"name":"School of Medicine Adelaide University  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,21]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001681"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428\u2010023\u201003529\u20104"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428\u2010021\u201003027\u20103"},{"key":"e_1_2_9_5_1","volume-title":"WHO Classification of Tumours: Skin Tumours","author":"WHO Classification of Tumours Editorial Board","year":"2025"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428\u2010024\u201003516\u20103"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14508"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.49.33042"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkh571"}],"container-title":["Genes, Chromosomes and Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/gcc.70099","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/gcc.70099","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/gcc.70099","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T12:55:53Z","timestamp":1769604953000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/gcc.70099"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/gcc.70099"],"URL":"https:\/\/doi.org\/10.1002\/gcc.70099","archive":["Portico"],"relation":{},"ISSN":["1045-2257","1098-2264"],"issn-type":[{"value":"1045-2257","type":"print"},{"value":"1098-2264","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-09-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70099"}}