{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:51:09Z","timestamp":1791471069991,"version":"4.3.4"},"reference-count":14,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:00:00Z","timestamp":1791417600000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100011892","name":"Kaohsiung Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPG8N0891"],"award-info":[{"award-number":["CMRPG8N0891"]}],"id":[{"id":"10.13039\/501100011892","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Genes Chromosomes &amp;amp; Cancer"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>MN1::BEND2<\/jats:italic>\n                    fusion is well established in CNS tumors but exceptionally rare in extracranial mesenchymal neoplasms. We report a subcutaneous upper\u2010back tumor in a 41\u2010year\u2010old woman, composed of bland round\u2010to\u2010epithelioid cells with branching capillary vasculature and focal infiltrative growth. The tumor recurred 42\u2009months after excision. Targeted RNA sequencing identified an in\u2010frame\n                    <jats:italic>MN1<\/jats:italic>\n                    exon 1::\n                    <jats:italic>BEND2<\/jats:italic>\n                    exon 9 fusion, supported by Sanger sequencing and\n                    <jats:italic>MN1<\/jats:italic>\n                    break\u2010apart FISH; Nuclear BEND2 immunoreactivity was an ancillary finding. Unlike two previously reported extracranial\n                    <jats:italic>MN1::BEND2<\/jats:italic>\n                    \u2010harboring tumors with high\u2010grade spindle\u2010cell morphology and myofibroblastic differentiation, this tumor lacked overt high\u2010grade nuclear features and myoid differentiation. This case broadens the morphologic spectrum of\n                    <jats:italic>MN1::BEND2<\/jats:italic>\n                    mesenchymal neoplasms. Limited reported cases, no meaningful follow\u2010up after re\u2010excision, and unsuccessful methylation profiling preclude conclusions regarding biologic behavior. BEND2 immunohistochemistry may serve an ancillary screen marker, but its sensitivity and specificity remain to be established, and molecular confirmation is required.\n                  <\/jats:p>","DOI":"10.1002\/gcc.70180","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:02:27Z","timestamp":1791468147000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Round\u2010to\u2010Epithelioid Mesenchymal Tumor Harboring an\n                    <i>MN1::BEND2<\/i>\n                    Fusion: Expanding the Morphologic Spectrum"],"prefix":"10.1002","volume":"65","author":[{"given":"Qiong\u2010Yi","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Anatomic Pathology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ko\u2010Chin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pathology Tainan Municipal Hospital  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan\u2010Shan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pathology Chi Mei Medical Center  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fu\u2010Chen","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1216-7751","authenticated-orcid":false,"given":"Hsuan\u2010Ying","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine  Kaohsiung 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