{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T21:58:52Z","timestamp":1772575132213,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1704,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genet. Epidemiol."],"published-print":{"date-parts":[[2011]]},"DOI":"10.1002\/gepi.20605","type":"journal-article","created":{"date-parts":[[2011,7,18]],"date-time":"2011-07-18T18:15:28Z","timestamp":1311012928000},"page":"n\/a-n\/a","source":"Crossref","is-referenced-by-count":11,"title":["A risk prediction algorithm based on family history and common genetic variants: application to prostate cancer with potential clinical impact"],"prefix":"10.1002","author":[{"given":"Robert J.","family":"MacInnis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonis C.","family":"Antoniou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosalind A.","family":"Eeles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca","family":"Severi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Amin","family":"Al Olama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lesley","family":"McGuffog","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsofia","family":"Kote-Jarai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Guy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynne T.","family":"O'Brien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda L.","family":"Hall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosemary A.","family":"Wilkinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma","family":"Sawyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Audrey T.","family":"Ardern-Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David P.","family":"Dearnaley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Horwich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent S.","family":"Khoo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher C.","family":"Parker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Huddart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Van As","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret R.","family":"McCredie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dallas R.","family":"English","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham G.","family":"Giles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John L.","family":"Hopper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas F.","family":"Easton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,7,18]]},"reference":[{"key":"10.1002\/gepi.20605-BIB1|cit1","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1038\/sj.bjc.6603929","article-title":"Rare germline mutations in the BRCA2 gene are associated with early-onset prostate cancer","volume":"97","author":"Agalliu","year":"2007","journal-title":"Br J Cancer"},{"key":"10.1002\/gepi.20605-BIB2|cit2","volume-title":"Cancer in Australia: An Overview, 2006","author":"AIHW (Australian Institute of Health and Welfare) & AACR (Australasian Association of Cancer Registries)","year":"2007"},{"key":"10.1002\/gepi.20605-BIB3|cit3","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1109\/TAC.1974.1100705","article-title":"A new look at the statistical model identification","volume":"19","author":"Akaike","year":"1974","journal-title":"IEEE Trans Automat Control"},{"key":"10.1002\/gepi.20605-BIB4|cit4","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1038\/ng.452","article-title":"Multiple loci on 8q24 associated with prostate cancer susceptibility","volume":"41","author":"Al Olama","year":"2009","journal-title":"Nat Genet"},{"key":"10.1002\/gepi.20605-BIB5|cit5","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1056\/NEJMoa0810696","article-title":"Mortality results from a randomized prostate-cancer screening trial","volume":"360","author":"Andriole","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1002\/gepi.20605-BIB6|cit6","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/gepi.10261","article-title":"Polygenic inheritance of breast cancer: implications for design of association studies","volume":"25","author":"Antoniou","year":"2003","journal-title":"Genet Epidemiol"},{"key":"10.1002\/gepi.20605-BIB7|cit7","doi-asserted-by":"crossref","first-page":"257","DOI":"10.2217\/14796694.2.2.257","article-title":"Risk prediction models for familial breast cancer","volume":"2","author":"Antoniou","year":"2006","journal-title":"Future Oncol"},{"key":"10.1002\/gepi.20605-BIB8|cit8","doi-asserted-by":"crossref","first-page":"R109","DOI":"10.1093\/hmg\/ddn287","article-title":"Genome-wide association studies in cancer","volume":"17","author":"Easton","year":"2008","journal-title":"Hum Mol Genet"},{"key":"10.1002\/gepi.20605-BIB9|cit9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/345310","article-title":"Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene","volume":"72","author":"Edwards","year":"2003","journal-title":"Am J Hum Genet"},{"key":"10.1002\/gepi.20605-BIB10|cit10","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1038\/ng.450","article-title":"Identification of seven new prostate cancer susceptibility loci through a genome-wide association study","volume":"41","author":"Eeles","year":"2009","journal-title":"Nat Genet"},{"key":"10.1002\/gepi.20605-BIB11|cit11","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/978-3-642-74487-7_3","volume-title":"Advances in Statistical Methods for Genetic Improvement of Livestock","author":"Elston","year":"1990"},{"key":"10.1002\/gepi.20605-BIB12|cit12","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/BF01240920","article-title":"The finite polygenic mixed model: an alternative formulation for the mixed model of inheritance","volume":"88","author":"Fernando","year":"1994","journal-title":"Theor Appl Genet"},{"key":"10.1002\/gepi.20605-BIB13|cit13","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1093\/jnci\/dji128","article-title":"Cancer risk prediction models: a workshop on development, evaluation, and application","volume":"97","author":"Freedman","year":"2005","journal-title":"J Natl Cancer Inst"},{"key":"10.1002\/gepi.20605-BIB14|cit14","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1023\/A:1011131105617","article-title":"Smoking and prostate cancer: findings from an Australian case-control study","volume":"12","author":"Giles","year":"2001","journal-title":"Ann Oncol"},{"key":"10.1002\/gepi.20605-BIB15|cit15","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1038\/ng2062","article-title":"Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes","volume":"39","author":"Gudmundsson","year":"2007","journal-title":"Nat Genet"},{"key":"10.1002\/gepi.20605-BIB16|cit16","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/ng.89","article-title":"Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer","volume":"40","author":"Gudmundsson","year":"2008","journal-title":"Nat Genet"},{"key":"10.1002\/gepi.20605-BIB17|cit17","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1046\/j.1464-410X.2003.04232.x","article-title":"A systematic review and meta-analysis of familial prostate cancer risk","volume":"91","author":"Johns","year":"2003","journal-title":"BJU Int"},{"key":"10.1002\/gepi.20605-BIB18|cit18","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1158\/1055-9965.EPI-08-0317","article-title":"Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium","volume":"17","author":"Kote-Jarai","year":"2008","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1002\/gepi.20605-BIB19|cit19","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1093\/genetics\/147.3.1423","article-title":"An approximate model of polygenic inheritance","volume":"147","author":"Lange","year":"1997","journal-title":"Genetics"},{"key":"10.1002\/gepi.20605-BIB20|cit20","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/gepi.1370050611","article-title":"Programs for Pedigree Analysis: MENDEL, FISHER, and dGENE","volume":"5","author":"Lange","year":"1988","journal-title":"Genet Epidemiol"},{"key":"10.1002\/gepi.20605-BIB21|cit21","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/gepi.20433","article-title":"Prostate cancer segregation analyses using 4390 families from UK and Australian population-based studies","volume":"34","author":"MacInnis","year":"2010","journal-title":"Genet Epidemiol"},{"key":"10.1002\/gepi.20605-BIB22|cit22","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1038\/sj.bjc.6604132","article-title":"Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype","volume":"98","author":"Mitra","year":"2008","journal-title":"Br J Cancer"},{"key":"10.1002\/gepi.20605-BIB23|cit23","volume-title":"Cancer Statistics-Registrations, England, 2004","author":"Office for National Statistics","year":"2006"},{"key":"10.1002\/gepi.20605-BIB24|cit24","unstructured":"Parkin DM Whelan SL Ferlay J Teppo L Thomas DB 2003 Cancer Incidence in Five Continents"},{"key":"10.1002\/gepi.20605-BIB25|cit25","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1056\/NEJMoa0810084","article-title":"Screening and prostate-cancer mortality in a randomized European study","volume":"360","author":"Schroder","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1002\/gepi.20605-BIB26|cit26","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1093\/jnci\/91.15.1310","article-title":"Cancer risks in BRCA2 mutation carriers","volume":"91","author":"The Breast Cancer Linkage Consortium","year":"1999","journal-title":"J Natl Cancer Inst"},{"key":"10.1002\/gepi.20605-BIB27|cit27","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1093\/jnci\/djm005","article-title":"Prostate cancer progression and survival in BRCA2 mutation carriers","volume":"99","author":"Tryggvadottir","year":"2007","journal-title":"J Natl Cancer Inst"},{"key":"10.1002\/gepi.20605-BIB28|cit28","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1158\/1078-0432.CCR-07-5237","article-title":"Loss of heterozygosity at the BRCA2 locus detected by multiplex ligation-dependent probe amplification is common in prostate cancers from men with a germline BRCA2 mutation","volume":"14","author":"Willems","year":"2008","journal-title":"Clin Cancer Res"},{"key":"10.1002\/gepi.20605-BIB29|cit29","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/nrg2507","article-title":"Prostate cancer genomics: towards a new understanding","volume":"10","author":"Witte","year":"2009","journal-title":"Nat Rev Genet"},{"key":"10.1002\/gepi.20605-BIB30|cit30","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1056\/NEJMoa075819","article-title":"Cumulative association of five genetic variants with prostate cancer","volume":"358","author":"Zheng","year":"2008","journal-title":"N Engl J Med"}],"container-title":["Genetic Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fgepi.20605","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/gepi.20605\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T20:44:55Z","timestamp":1712609095000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/gepi.20605"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":30,"URL":"https:\/\/doi.org\/10.1002\/gepi.20605","relation":{},"ISSN":["0741-0395"],"issn-type":[{"value":"0741-0395","type":"print"}],"subject":[],"published":{"date-parts":[[2011]]}}}