{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T14:44:02Z","timestamp":1777905842629,"version":"3.51.4"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T00:00:00Z","timestamp":1754870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical and Public Health Guidelines"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Chronic pain affects 1 in 5 adults and children globally; however, management remains highly variable and low value care is common. Inconsistent recommendations among clinical practice guidelines for management of chronic pain contribute to suboptimal patient management. We will develop and disseminate a living digital chronic pain recommendation map (e\u2010Chronic Pain RecMap) to identify trustworthy recommendations in three high priority areas, (1) opioids, (2) cannabis for medical purposes, and (3) spine\u2010related interventional procedures for chronic pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The project comprises three phases. A planning phase to engage a diverse group of interest holders to co\u2010design a team structure with our knowledge users to ensure an efficient and effective workflow. Through a search of electronic databases and a manual search of international websites, a development phase to systematically identify relevant guidelines published in any language since 2019. In this development phase, we will update our searches every 6 months. Also, we will appraise the reporting quality of eligible guidelines using the AGREE\u2010II instrument, followed by appraisal of recommendation\u2010level quality using AGREE\u2010REX for guidelines meeting a defined threshold. In a next step, we will extract data from guidelines including relevant equity information using infrastructure in GRADEPro, and explore divergence and compare recommendations answering the same guideline question. Lastly, we will develop plain language summaries of trustworthy recommendations and decision aids to support patient\u2010physician decision making, and translate the platform to French, Spanish, and Mandarin. Finally, a mobilization phase in which, with our interest holders, we will co\u2010create strategies to disseminate the RecMap to relevant target users.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The Chronic Pain RecMap will enhance use of trustworthy guideline recommendations by people living with chronic pain, clinicians, and decision makers. Successful uptake will optimize evidence\u2010based pain management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/gin2.70033","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T12:54:46Z","timestamp":1754916886000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Consolidation, Systematic Appraisal and Comparison of Guideline Recommendations Regarding Management of Chronic Pain: Protocol for a Digital Chronic Pain Recommendation Map"],"prefix":"10.1002","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2498-1697","authenticated-orcid":false,"given":"Andrea J.","family":"Darzi","sequence":"first","affiliation":[{"name":"Department of Health Research Methods, Evidence, and Impact McMaster University Hamilton Ontario Canada"},{"name":"Department of Anesthesia McMaster University Hamilton Ontario Canada"},{"name":"Michael G. DeGroote National Pain Center McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3520-245X","authenticated-orcid":false,"given":"Kian","family":"Torabiardakani","sequence":"additional","affiliation":[{"name":"Department of Anesthesia McMaster University Hamilton Ontario Canada"},{"name":"Michael G. DeGroote National Pain Center McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gonzalo","family":"Bravo\u2010Soto","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence, and Impact McMaster University Hamilton Ontario Canada"},{"name":"Michael G. DeGroote National Pain Center McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Montalva\u2010Romero","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence, and Impact McMaster University Hamilton Ontario Canada"},{"name":"Department of Anesthesia McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel J.","family":"Couban","sequence":"additional","affiliation":[{"name":"Michael G. DeGroote National Pain Center McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynn","family":"Cooper","sequence":"additional","affiliation":[{"name":"Michael G. DeGroote National Pain Center McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6192-182X","authenticated-orcid":false,"given":"Stacey","family":"Ritz","sequence":"additional","affiliation":[{"name":"Department of Pathology &amp; Molecular Medicine McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaris","family":"Swidrovich","sequence":"additional","affiliation":[{"name":"Leslie Dan Faculty of Pharmacy University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan D.","family":"Florez","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Antioquia Medellin Colombia"},{"name":"Pediatric Intensive Care Unit Cl\u0131nica Las Americas\u2010AUNA Medellin Colombia"},{"name":"School of Rehabilitation Science McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivian","family":"Welch","sequence":"additional","affiliation":[{"name":"Bruy\u00e8re Health Research Institute University of Ottawa Ottawa Ontario Canada"},{"name":"School of Epidemiology and Public Health University of Ottawa Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordon H.","family":"Guyatt","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence, and Impact McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3211-8479","authenticated-orcid":false,"given":"Holger J.","family":"Sch\u00fcnemann","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence, and Impact McMaster University Hamilton Ontario Canada"},{"name":"Clinical Epidemiology and Research Center (CERC) Humanitas University &amp; Humanitas Research Hospital Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason W.","family":"Busse","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence, and Impact McMaster University Hamilton Ontario Canada"},{"name":"Department of Anesthesia McMaster University Hamilton Ontario Canada"},{"name":"Michael G. 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