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By manipulating culture conditions, it is possible to induce Olig2 expression in rapidly dividing cells. These cells have many of the features of glial progenitor cells but, unlike other glial progenitors, are able to divide rapidly for at least 1 month while still expressing Olig2. Even after 1\u2010month expansion, the cells differentiate readily into astrocyte\u2010like and oligodendrocyte\u2010like cells when switched to serum\u2010containing medium. Cellular memory is the property whereby cells remain specified to a particular lineage or pathway while undergoing division. 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