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The concentration of metallothioneins, evaluated by immunohistochemistry, as well as area\u2010specific protein expression, were found in the following quantitative order: corpus striatum, cerebellum, mesencephalon, hippocampus with fornix, parts of thalamus, and pons. All other brain areas were marginally affected, or even unaffected, in terms of immunopositive metallothionein reaction. Metallothionein I\/II expression was compared with the immunopositivity of glial fibrillary acidic protein (GFAP). 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