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To elucidate the isoform expression pattern, specific antisera directed against the brain (BB) and muscle (MM) isoforms of GP were applied to retinal sections, isolated M\u00fcller cells, and sections of the optic nerve. We show that M\u00fcller cells of rat, rabbit, guinea pig, and mouse retina exclusively express the BB isoform. Astrocytes of rat and rabbit optic nerve, as well as retina express only the BB isoform. In contrast, astrocytes in the brain and spinal cord as well as the epithelial cells of the pars caeca and of the ciliary body express both the BB and MM isoform. This result may indicate some differences in the role of glycogen in retinal macroglia and brain astrocytes, reflecting a local specialization of macroglia in the retina proper. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/glia.20102","type":"journal-article","created":{"date-parts":[[2004,7,27]],"date-time":"2004-07-27T15:45:50Z","timestamp":1090943150000},"page":"84-95","source":"Crossref","is-referenced-by-count":45,"title":["Glycogen phosphorylase isozyme pattern in mammalian retinal M\u00fcller (glial) cells and in astrocytes of retina and optic 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