{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T05:55:45Z","timestamp":1791006945822,"version":"4.1.0"},"reference-count":13,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2008,5,23]],"date-time":"2008-05-23T00:00:00Z","timestamp":1211500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To estimate the projected population of US adults aged 18 years or older with lifetime experience of doctor\u2010diagnosed depressive disorder from 2005\u20132050.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Based on nationally representative survey data from the year 2006 Behavioral Risk Factor Surveillance Survey (BRFSS), prevalence estimates of doctor\u2010diagnosed depression (minor or major, and dysthymia) were weighted to incorporate the complex sampling design and increase generalizability of the findings. The weighted prevalence data by age and sex in 2006 were then used to estimate the projected adult population with lifetime experience of depressive disorder based on the sex\u2010specific US Census national population projections from year 2005\u20132050.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In year 2006 the (weighted) prevalence of lifetime experience of depressive disorder was 15.7% among 188,292 respondents aged 18 years or older. Female prevalence was 20.6%, which was about twice as high as the prevalence among males (11%). From year 2005\u20132050, the total number of US adults with depressive disorder will increase from 33.9 million to 45.8 million, a 35% increase. The increase is projected to be greater in the elderly population aged \u226565 years (3.8\u20138.2, a 117% increase) than in the young population aged &lt;65 years (30.1\u201337.7, a 25% increase).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>By year 2050, approximately 46 million US adults aged 18 years or older will be diagnosed with a depressive disorder. The increase will be more pronounced in adults aged 65 or older. Prevention, detection, and treatment of depressive disorders might attenuate the magnitude of this estimate. Copyright \u00a9 2008 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/gps.2061","type":"journal-article","created":{"date-parts":[[2008,5,23]],"date-time":"2008-05-23T16:22:38Z","timestamp":1211559758000},"page":"1266-1270","source":"Crossref","is-referenced-by-count":72,"title":["Population projection of US adults with lifetime experience of depressive disorder by age and sex from year 2005 to 2050"],"prefix":"10.1002","volume":"23","author":[{"given":"Moonseong","family":"Heo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher F.","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin R.","family":"Fontaine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha L.","family":"Bruce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George S.","family":"Alexopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,5,23]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66665-2"},{"key":"e_1_2_1_3_1","volume-title":"Behavioral Risk Factor Surveillance System Survey Data","author":"Centers for Disease Control and Prevention (CDC)","year":"2006"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.153.8.1001"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(01)00413-X"},{"key":"e_1_2_1_6_1","volume-title":"Population Projections of the United States by Age, Sex, Race, and Hispanic Origin: 1995 to 2050","author":"Day J.","year":"1996"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2007.01017.x"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)67964-6"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0749-3797(18)31372-2","article-title":"The behavioral risk factor surveys: II Design, methods, and estimates from combined state data","volume":"1","author":"Gentry EM","year":"1985","journal-title":"Am J Prev Med"},{"key":"e_1_2_1_10_1","volume-title":"Methodology and Assumptions for the Population Projections of the United States: 1999 to 2100","author":"Hollman FW","year":"2000"},{"key":"e_1_2_1_11_1","unstructured":"Population Projections Bureau Population Division US Census Bureau.2000.Summary File (NP\u2010T3): Projections of the Total Resident Population by 5\u2010year Age Groups and Sex with Special Age Categories: Middle Series. Available atwww.census.gov\/population\/www\/projections\/natsum\u2010T3.html."},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.3.479"},{"key":"e_1_2_1_13_1","volume-title":"Healthy People 2010: Understanding and Improving Health","author":"US Department of Health and Human Services","year":"2000"},{"key":"e_1_2_1_14_1","volume-title":"The Road Ahead: Research Partnerships to Transform Services","author":"US Department of Health and Human Services","year":"2006"}],"container-title":["International Journal of Geriatric Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fgps.2061","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/gps.2061","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T09:58:30Z","timestamp":1700042310000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/gps.2061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5,23]]},"references-count":13,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["10.1002\/gps.2061"],"URL":"https:\/\/doi.org\/10.1002\/gps.2061","archive":["Portico"],"relation":{},"ISSN":["0885-6230","1099-1166"],"issn-type":[{"value":"0885-6230","type":"print"},{"value":"1099-1166","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5,23]]}}}