{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T10:33:40Z","timestamp":1791110020040,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,10,5]],"date-time":"2009-10-05T00:00:00Z","timestamp":1254700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>In primary care 50\u201395% of patients with depression present with vegetative symptoms (VS). Based on the extant literature, older adults showing VS (but no dysphoria) may show functional impairment but this hypothesis has not been empirically tested. The goal of this study was to examine neurocognitive and daily functioning of elderly patients showing exclusively VS in comparison with patients presenting with VS and dysphoria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seven hundred and eighty\u2010seven primary care patients received measures of neurocognition and daily functioning. Neurocognition was measured with the repeatable battery for the assessment of neuropsychological status (RBANS). Three groups were compared: (1) patients with two or more VS of depression without dysphoria (VS\u2009\u2212\u2009D), (2) patients with at least one VS and dysphoria (VS\u2009+\u2009D), and (3) comparison patients without multiple VS or dysphoria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nearly one third of the sample (31%) fell into the VS\u2009\u2212\u2009D group, whereas 15% fell into the VS\u2009+\u2009D group. Both VS groups showed poorer neurocognition and activities of daily living than comparisons. Only one subtest of the RBANS (i.e., picture naming) showed a significant difference between VS\u2009+\u2009D and VS\u2009\u2212\u2009D, and there was no significant difference on daily functioning. VS\u2009\u2212\u2009D patients reported less frequent past history of depression and endorsed less anxiety compared to VS\u2009+\u2009D.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Elderly patients presenting with clusters of VS with or without dysphoria show poorer neurocognitive and functional performance. Relative poorer cognition and daily functioning in VS\u2009\u2212\u2009D are potential harbingers of further decline and consistent with under\u2010reporting of sadness in older age. Copyright \u00a9 2009 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/gps.2376","type":"journal-article","created":{"date-parts":[[2009,10,5]],"date-time":"2009-10-05T13:22:55Z","timestamp":1254748975000},"page":"569-577","source":"Crossref","is-referenced-by-count":16,"title":["Cognitive and daily functioning in older adults with vegetative symptoms of depression"],"prefix":"10.1002","volume":"25","author":[{"given":"Sergio","family":"Paradiso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Duff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jatin G.","family":"Vaidya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Hoth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James W.","family":"Mold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,10,5]]},"reference":[{"key":"e_1_2_1_2_1","volume-title":"American Psychiatric Association: Diagnostic criteria from DSM\u2010IV\u2010TR","author":"American Psychiatric Association","year":"2000"},{"key":"e_1_2_1_3_1","first-page":"4","article-title":"The nature of painful and somatic complaints in depressive disorders","volume":"10","author":"Arnold LM","year":"2005","journal-title":"CNS Spectr"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0327(92)90089-O"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.genhosppsych.2005.10.001"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03450190056028"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(03)00473-6"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr050982w"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.7.664"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610207006187"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.JGP.0000229690.70011.cd"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1076\/clin.17.3.351.18082"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1984.03350140051025"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.12.1570"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291798008083"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1997.tb03089.x"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02596483"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000117631"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.154.2.201"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38683.710255.BE"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000285676"},{"key":"e_1_2_1_22_1","first-page":"18","article-title":"Subsyndromal symptomatic depression: a new mood disorder?","volume":"55","author":"Judd LL","year":"1994","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2006.8.2\/hpkapfhammer"},{"key":"e_1_2_1_24_1","volume-title":"Masked Depression","author":"Keilholz P","year":"1973"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-3182(93)71926-X"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-198711000-00006"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-192104000-00057"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.7.1119"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-7-200604040-00008"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0193-953X(03)00106-0"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/51A.4.M172"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0327(96)00059-6"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.70.2.180"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-199712000-00005"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.neuropsych.20.1.52"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/JGP.0b013e31817e73b0"},{"key":"e_1_2_1_37_1","first-page":"787","article-title":"Manic depressive psychosis in private practice","volume":"23","author":"Paskind H","year":"1930","journal-title":"Arch Neurol Psychiatry"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.21.1720"},{"key":"e_1_2_1_39_1","volume-title":"The Repeatable Battery for the Assessment of Neuropsychological Status","author":"Randolph C","year":"1998"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1985.01790240091010"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199910283411801"},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019442-199908000-00008"},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2000.tb06882.x"}],"container-title":["International Journal of Geriatric Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fgps.2376","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/gps.2376","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T14:16:04Z","timestamp":1700576164000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/gps.2376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10,5]]},"references-count":42,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["10.1002\/gps.2376"],"URL":"https:\/\/doi.org\/10.1002\/gps.2376","archive":["Portico"],"relation":{},"ISSN":["0885-6230","1099-1166"],"issn-type":[{"value":"0885-6230","type":"print"},{"value":"1099-1166","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10,5]]}}}