{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T18:48:46Z","timestamp":1777574926400,"version":"3.51.4"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2010,12,7]],"date-time":"2010-12-07T00:00:00Z","timestamp":1291680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Anxiety symptoms are highly prevalent in elders with mild cognitive disorders, but little is known about the associations of specific anxiety disorders to mild cognitive disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To identify the clinical and subclinical anxiety disorders associated with cognitive impairment no dementia (CIND) and to determine whether these associations differ depending on sex and concomitant depressive episodes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Participants constituted a random sample (<jats:italic>n<\/jats:italic>\u2009=\u20092414) of community\u2010dwelling adults aged 65\u201396 years. The following clinical and subclinical DSM\u2010IV anxiety disorders were identified with a semi\u2010structured interview: specific phobia, social phobia, agoraphobia, panic disorder, obsessive\u2013compulsive, and generalized anxiety disorder (GAD). Major depressive episodes or minor depression (MDE\/MD) were also determined based on the DSM\u2010IV criteria. CIND cases were defined based on Mini\u2010Mental State Examination (MMSE) cut\u2010offs (15th percentile) stratified for age, education, and sex. Potentially confounding variables (age, education, MDE\/MD, chronic diseases, and psychotropic drug use) were statistically controlled.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In men, after adjusting for confounding variables, CIND was associated with subclinical GAD (odds ratio (OR): 4.93, 95% confidence interval: 1.84\u201313.23). Further analyses showed that in men, CIND was related to clinical\/subclinical GAD whether MDE\/MD was present (7.05, 1.88\u201326.43) or absent (9.33, 3.24\u201326.83). In women, CIND was not linked to any clinical or subclinical anxiety disorder.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These results suggest that in community\u2010dwelling elders, GAD is the main anxiety disorder associated with poor global cognitive functioning. Moreover, this association is modified by sex, but not by the presence of depressive episodes. 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