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Double\u2010blind, randomized controlled trials of statins given for at least 6\u2009months in people with a diagnosis of dementia were included. Two independent authors extracted and assessed data independently against the inclusion criteria. Data were pooled where appropriate and entered into a meta\u2010analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three studies were identified (748 participants, age range 50\u201390\u2009years). All patients had a diagnosis of probable or possible Alzheimer's disease according to standard criteria, and most patients were established on a cholinesterase inhibitor. Change in Alzheimer's Disease Assessment Scale cognitive subscale from baseline was a primary outcome in three studies; when data were pooled, statins did not provide any beneficial effect in this cognitive measure (mean difference \u22121.12; 95% confidence interval \u22123.99, 1.75; <jats:italic>p<\/jats:italic>\u2009=\u20090.44). All studies provided a change in Mini\u2010Mental State Examination from baseline; there was no significant benefit from statins in this cognitive measure when the data were pooled (mean difference \u22121.53; 95% confidence interval \u22123.28; 0.21, <jats:italic>p<\/jats:italic>\u2009=\u20090.08). There were no studies identified assessing the role of statins in treatment of vascular dementia. There was no evidence that statins were detrimental to cognition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There is insufficient evidence to recommend statins for the treatment of dementia. 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