{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T23:09:50Z","timestamp":1778713790653,"version":"3.51.4"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,8,12]],"date-time":"2014-08-12T00:00:00Z","timestamp":1407801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"PACE Program, Pennsylvania Department of Aging"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The objective of this study is to understand the characteristics of older adults on newly prescribed psychotropic medication with minimal psychiatric symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Naturalistic cohort study of non\u2010institutionalized older adults in Pennsylvania participating in the Pharmaceutical Assistance Contract for the Elderly. Persons newly prescribed antidepressant or anxiolytic monotherapy or combination therapy were contacted for clinical assessment by a telephone\u2010based behavioral health service. The initial assessment included standardized mental health screening instruments and scales including the Blessed Orientation\u2010Memory\u2010Concentration test, Patient Health Questionnaire\u20109, Generalized Anxiety Disorder\u20107, and Medical Outcomes Survey (SF\u201012). In addition, patients were asked for their understanding of the prescription indication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 254 participants who met minimal symptom criteria (Patient Health Questionnaire\u20109\u2009&lt;\u20095 and Generalized Anxiety Disorder\u20107\u2009&lt;\u20095), women comprised slightly more of the anxiolytic compared with antidepressant monotherapy group (88.9% vs. 76.7%, <jats:italic>p<\/jats:italic>\u2009=\u20090.04). The most common self\u2010reported reason for prescription of an antidepressant or anxiolytic was depression or anxiety, respectively, despite near\u2010absence of these symptoms on clinical assessment. Comparing monotherapy to combination therapy groups, those with combination therapy were more likely to report a history of depression (12.6% vs. 1.8%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and also report depression as the reason for the prescription (40.2% vs. 21.0%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this sample of older adults on new psychotropic medication with minimal psychiatric symptoms, there are few patient characteristics that distinguish those on antidepressant versus anxiolytic monotherapy or those on monotherapy versus combination therapy. While quality of care in late\u2010life mental health has focused on improving detection and treatment, there should be further attention to low\u2010symptom patients potentially receiving inappropriate pharmacotherapy. Copyright \u00a9 2014 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/gps.4187","type":"journal-article","created":{"date-parts":[[2014,8,13]],"date-time":"2014-08-13T13:25:32Z","timestamp":1407936332000},"page":"580-586","source":"Crossref","is-referenced-by-count":6,"title":["Older adults recently started on psychotropic medication: where are the symptoms?"],"prefix":"10.1002","volume":"30","author":[{"given":"Donovan T.","family":"Maust","sequence":"first","affiliation":[{"name":"Department of Psychiatry University of Michigan  Ann Arbor MI USA"},{"name":"Center for Clinical Management Research VA Ann Arbor Healthcare System  Ann Arbor MI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shirley H.","family":"Chen","sequence":"additional","affiliation":[{"name":"Philadelphia Veterans Affairs Medical Center and the VISN 4 Mental Illness Research, Education, and Clinical Center (MIRECC)  Philadelphia PA 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