{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:35:59Z","timestamp":1770510959782,"version":"3.49.0"},"reference-count":41,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,11,2]],"date-time":"2015-11-02T00:00:00Z","timestamp":1446422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014934","name":"Avanir Pharmaceuticals, Inc.","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100014934","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Pseudobulbar affect (PBA) is a neurological disorder of emotional expression, characterized by uncontrollable episodes of crying or laughing in patients with certain neurological disorders affecting the brain. The purposes of this study were to estimate the prevalence of PBA in US nursing home residents and examine the relationship between PBA symptoms and other clinical correlates, including the use of psychopharmacological medications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study was conducted between 2013 and 2014 with a convenience sample of residents from nine Michigan nursing homes. Chronic\u2010care residents were included in the \u201cpredisposed population\u201d if they had a neurological disorder affecting the brain and no evidence of psychosis, delirium, or disruptive behavior (per chart review). Residents were screened for PBA symptoms by a geropsychologist using the Center for Neurologic Study\u2010Lability Scale (CNS\u2010LS). Additional clinical information was collected using a diagnostic evaluation checklist and the most recent Minimum Data Set 3.0 assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 811 residents screened, complete data were available for 804, and 412 (51%) met the criteria for the \u201cpredisposed population.\u201d PBA symptom prevalence, based on having a CNS\u2010LS score \u226513, was 17.5% in the predisposed population and 9.0% among all nursing home residents. Those with PBA symptoms were more likely to have a documented mood disorder and be using a psychopharmacological medication, including antipsychotics, than those without PBA symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Pseudobulbar affect symptoms were present in 17.5% of nursing home residents with neurological conditions, and 9.0% of residents overall. Increasing awareness and improving diagnostic accuracy of PBA may help optimize treatment. \u00a9 2015 The Authors. <jats:italic>International Journal of Geriatric Psychiatry<\/jats:italic> Published by John Wiley &amp; Sons Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/gps.4374","type":"journal-article","created":{"date-parts":[[2015,11,3]],"date-time":"2015-11-03T02:38:55Z","timestamp":1446518335000},"page":"694-701","source":"Crossref","is-referenced-by-count":8,"title":["Prevalence of pseudobulbar affect symptoms and clinical correlates in nursing home residents"],"prefix":"10.1002","volume":"31","author":[{"given":"Kevin","family":"Foley","sequence":"first","affiliation":[{"name":"College of Human Medicine Michigan State University  East Lansing MI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. Tamara","family":"Konetzka","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences University of Chicago  Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Bunin","sequence":"additional","affiliation":[{"name":"Behavioral Care Solutions  Warren MI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Yonan","sequence":"additional","affiliation":[{"name":"Avanir Pharmaceuticals, Inc.  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