{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T18:40:12Z","timestamp":1773772812021,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study is to evaluate the effect of a high\u2010intensity functional exercise program on depressive symptoms among older care facility residents with dementia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Residents (<jats:italic>n<\/jats:italic>\u2009=\u2009186) with a diagnosis of dementia, age\u2009\u2265\u200965\u2009years, Mini\u2010Mental State Examination score\u2009\u2265\u200910, and dependence in activities of daily living were included. Participants were randomized to a high\u2010intensity functional exercise program or a non\u2010exercise control activity conducted 45\u2009min every other weekday for 4\u2009months. The 15\u2010item Geriatric Depression Scale (GDS) and the Montgomery\u2013\u00c5sberg Depression Rating Scale (MADRS) were administered by blinded assessors at baseline, 4, and 7\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No difference between the exercise and control activity was found in GDS or MADRS score at 4 or 7\u2009months. Among participants with GDS scores\u2009\u2265\u20095, reductions in GDS score were observed in the exercise and control groups at 4\u2009months (\u20131.58, <jats:italic>P<\/jats:italic>\u2009=\u20090.001 and \u20131.54, <jats:italic>P<\/jats:italic>\u2009=\u20090.004) and 7\u2009months (\u20131.25, <jats:italic>P<\/jats:italic>\u2009=\u20090.01 and \u20131.45, <jats:italic>P<\/jats:italic>\u2009=\u20090.007). Among participants with MADRS scores\u2009\u2265\u20097, a reduction in MADRS score was observed at 4\u2009months in the control group (\u20132.80, <jats:italic>P<\/jats:italic>\u2009=\u20090.009) and at 7\u2009months in the exercise and control groups (\u20133.17, <jats:italic>P<\/jats:italic>\u2009=\u20090.003 and \u20133.34, <jats:italic>P<\/jats:italic>\u2009=\u20090.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A 4\u2010month high\u2010intensity functional exercise program has no superior effect on depressive symptoms relative to a control activity among older people with dementia living in residential care facilities. Exercise and non\u2010exercise group activities may reduce high levels of depressive symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1002\/gps.4401","type":"journal-article","created":{"date-parts":[[2015,12,9]],"date-time":"2015-12-09T01:57:55Z","timestamp":1449626275000},"page":"868-878","source":"Crossref","is-referenced-by-count":30,"title":["Effects of a high\u2010intensity functional exercise program on depressive symptoms among people with dementia in residential care: a randomized controlled trial"],"prefix":"10.1002","volume":"31","author":[{"given":"Gustaf","family":"Bostr\u00f6m","sequence":"first","affiliation":[{"name":"Department of Community Medicine and Rehabilitation, Geriatric Medicine Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mia","family":"Conradsson","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation, Geriatric Medicine Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl","family":"H\u00f6rnsten","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation, Geriatric Medicine Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"Rosendahl","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation, Geriatric Medicine Ume\u00e5 University  Ume\u00e5 Sweden"},{"name":"Department of Community Medicine and Rehabilitation, Physiotherapy Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Lindel\u00f6f","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation, Geriatric Medicine Ume\u00e5 University  Ume\u00e5 Sweden"},{"name":"Department of Community Medicine and Rehabilitation, Physiotherapy Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Holmberg","sequence":"additional","affiliation":[{"name":"Department of Public Health and Clinical Medicine Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Nordstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation, Geriatric Medicine Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yngve","family":"Gustafson","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation, Geriatric Medicine Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e5kan","family":"Littbrand","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation, Geriatric Medicine Ume\u00e5 University  Ume\u00e5 Sweden"},{"name":"Department of Community Medicine and Rehabilitation, Physiotherapy Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,12,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/44.4.P124"},{"key":"e_1_2_8_3_1","volume-title":"Diagnostic and statistical manual of mental disorders: DSM\u2010IV\u2010TR","author":"American Psychiatric Association","year":"2000"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1166(199606)11:6<507::AID-GPS337>3.0.CO;2-U"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60830-1"},{"key":"e_1_2_8_6_1","unstructured":"BatesD MaechlerM BolkerB et al.2013.lme4:Linear mixed\u2010effects models using Eigen and S4. 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