{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T21:28:57Z","timestamp":1792186137379,"version":"4.4.0"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,3,14]],"date-time":"2016-03-14T00:00:00Z","timestamp":1457913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Australian National Health and Medical Research Council","award":["351220"],"award-info":[{"award-number":["351220"]}]},{"name":"Australian National Health and Medical Research Council","award":["510745"],"award-info":[{"award-number":["510745"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>General practitioners (GPs) fail to identify more than 50% of dementia cases using the existing passive case\u2010finding approach. Using data from the \u201cAgeing in General Practice\u201d study, we sought to establish the additional benefit of screening all patients over the age of 75 for dementia beyond those patients already identified by passive case\u2010finding.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Patients were classified as \u201ccase\u2010finding\u201d (<jats:italic>n<\/jats:italic>= 425) or \u201cscreening\u201d (<jats:italic>n<\/jats:italic>= 1006) based on their answers to four subjective memory related questions or their GP's clinical judgement of their dementia status. Cognitive status of each patient was formally assessed by a research nurse using the Cambridge Cognition Examination (CAMCOG\u2010R). Patients then attended their usual GP for administration of the GP assessment of Cognition (GPCOG) dementia screening instrument, and follow\u2010up care and\/or referral as necessary in light of the outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of dementia was significantly higher in the case\u2010finding group (13.6%) compared to the screening group (4.6%;<jats:italic>p<\/jats:italic>&lt; 0.01). The GPCOG had a positive predictive value (PPV) of 61% in the case\u2010finding group and 39% in the screening group; negative predictive value was &gt;95% in both groups. GPs and their patients both found the GPCOG to be an acceptable cognitive assessment tool. The dementia cases missed via case\u2010finding were younger (<jats:italic>p<\/jats:italic>= 0.024) and less cognitively impaired (<jats:italic>p<\/jats:italic>= 0.020) than those detected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There is a very limited benefit of screening for dementia, as most people with dementia could be detected using a case\u2010finding approach, and considerable potential for social and economic harm because of the low PPV associated with screening.<\/jats:p><\/jats:sec>","DOI":"10.1002\/gps.4466","type":"journal-article","created":{"date-parts":[[2016,3,18]],"date-time":"2016-03-18T11:35:19Z","timestamp":1458300919000},"page":"316-323","source":"Crossref","is-referenced-by-count":11,"title":["An evaluation of the additional benefit of population screening for dementia beyond a passive case\u2010finding approach"],"prefix":"10.1002","volume":"32","author":[{"given":"Karen E.","family":"Mate","sequence":"first","affiliation":[{"name":"School of Biomedical Sciences and Pharmacy University of Newcastle NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parker J.","family":"Magin","sequence":"additional","affiliation":[{"name":"School of Medicine and Public Health University of Newcastle NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Brodaty","sequence":"additional","affiliation":[{"name":"Dementia Collaborative Research Centre and Centre for Healthy Brain Ageing, School of Psychiatry University of New South Wales NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel P.","family":"Stocks","sequence":"additional","affiliation":[{"name":"Discipline of General Practice, School of Population Health The University of Adelaide SA Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Gunn","sequence":"additional","affiliation":[{"name":"Department of General Practice The University of Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter B.","family":"Disler","sequence":"additional","affiliation":[{"name":"School of Rural Health Monash University Bendigo VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John E.","family":"Marley","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Pharmacy University of Newcastle NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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