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However, suicidal behavior is clinically and psychologically heterogeneous. Does a high level of perceived burdensomeness differentiate medically serious suicidal acts, most closely resembling death by suicide, from less serious ones? How is perceived burdensomeness related to dysfunctional personality dimensions implicated in suicide? We sought to answer these questions in a cross\u2010sectional, case\u2013control study of adults, aged 42\u2009years or older (<jats:italic>n<\/jats:italic>\u2009=\u2009165).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants were suicidal depressed with history of high\u2010lethality and low\u2010lethality attempts, depressed with serious suicidal ideation, depressed non\u2010suicidal, and psychiatrically healthy controls. Following detailed clinical characterization, we assessed perceived burdensomeness, the Big Five, impulsivity, and anger rumination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Low\u2010lethality attempters reported the highest levels of perceived burdensomeness, followed by ideators, high\u2010lethality attempters, non\u2010suicidal depressed, and healthy controls. Group differences were robust to confounders, including demographics, severity of depression, and physical illness burden. In suicide attempters, perceived burdensomeness scaled positively with neuroticism, impulsivity, and anger and negatively with extraversion, conscientiousness, and age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings suggest that perceived burdensomeness is most prominent in a subgroup of younger individuals with lower\u2010lethality suicide attempts and a dysfunctional interpersonal style. Older adults with high\u2010lethality attempts are surprisingly more resilient to the feelings of burdensomeness. Copyright \u00a9 2016 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/gps.4526","type":"journal-article","created":{"date-parts":[[2016,6,14]],"date-time":"2016-06-14T08:18:31Z","timestamp":1465892311000},"page":"788-797","source":"Crossref","is-referenced-by-count":30,"title":["Perceived burdensomeness is associated with low\u2010lethality suicide attempts, dysfunctional interpersonal style, and younger rather than older age"],"prefix":"10.1002","volume":"32","author":[{"given":"Polina M.","family":"Vanyukov","sequence":"first","affiliation":[{"name":"University of Pittsburgh School of Medicine Department of Psychiatry  Pittsburgh PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin","family":"Szanto","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine Department of Psychiatry  Pittsburgh PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Hallquist","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine Department of Psychiatry  Pittsburgh PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Modhurima","family":"Moitra","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine Department of Psychiatry  Pittsburgh PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre Y.","family":"Dombrovski","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine Department of Psychiatry  Pittsburgh PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11890"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-295X.97.1.90"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291701003889"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.132.3.285"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.47.2.343"},{"key":"e_1_2_9_7_1","first-page":"45","volume-title":"The Prediction of Suicide","author":"Beck AT","year":"1974"},{"key":"e_1_2_9_8_1","volume-title":"National Suicide Statistics at a Glance","author":"CDC","year":"2012"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-009-5115-0_5"},{"key":"e_1_2_9_10_1","volume-title":"The NEO\u2010PI\/NEO\u2010FFI Manual Supplement","author":"Costa PT","year":"1989"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0021836"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.337"},{"key":"e_1_2_9_13_1","first-page":"1020","article-title":"Reward signals, attempted suicide, and impulsivity in late\u2010life depression","volume":"70","author":"Dombrovski AY","year":"2013","journal-title":"J Am Med Assoc Psychiatry"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/JGP.0b013e3181860034"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2010.12.025"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291704002600"},{"key":"e_1_2_9_17_1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/geronb\/55.1.P18","article-title":"Personality traits and suicidal behavior and ideation in depressed inpatients 50\u2009years of age and older","volume":"55","author":"Duberstein PR","year":"2000","journal-title":"J Gerontol Psychol Sci"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0191-8869(96)00102-X"},{"key":"e_1_2_9_19_1","volume-title":"Structured Clinical Interview for DSM\u2010IV Axis I Disorders \u2013 Patient Edition (SCID\u2010I\/P). 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