{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:14:27Z","timestamp":1791357267608,"version":"4.3.1"},"reference-count":45,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T00:00:00Z","timestamp":1469059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Older adults with bipolar disorder (OABD) are a growing segment of patients with bipolar disorder (BD) for which specific guidelines are warranted. Although, OABD are frequently excluded from randomized controlled trials due to their age or somatic comorbidity, more treatment data from a variety of sources have become available in recent years. It is expected that at least some of this emerging information on OABD would be incorporated into treatment guidelines available to clinicians around the world.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The International Society of Bipolar Disorders OABD task force compiled and compared recommendations from current national and international guidelines that specifically address geriatric or older individuals with BD (from year 2005 onwards).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were 34 guidelines, representing six continents and 19 countries. The majority of guidelines had no separate section on OABD. General principles for treating OABD with medication are recommended to be similar to those for younger adults, with special caution for side effects due to somatic comorbidity and concomitant medications. Therapeutic lithium serum levels are suggested to be lower but recommendations are very general and mostly not informed by specific research evidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There is a lack of emphasis of OABD\u2010specific issues in existing guidelines. Given the substantial clinical heterogeneity in BD across the life span, along with the rapidly expanding population of older individuals worldwide, and limited mental health workforce with geriatric expertise, it is critical that additional effort and resources be devoted to studying treatment interventions specific to OABD and that treatment guidelines reflect research findings. Copyright \u00a9 2016 John Wiley &amp; Sons, Ltd.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/gps.4534","type":"journal-article","created":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T08:42:52Z","timestamp":1469090572000},"page":"1295-1300","source":"Crossref","is-referenced-by-count":65,"title":["Do current national and international guidelines have specific recommendations for older adults with bipolar disorder? A brief report"],"prefix":"10.1002","volume":"31","author":[{"given":"Annemiek","family":"Dols","sequence":"first","affiliation":[{"name":"Old Age Psychiatry, GGZinGeest VU Medical Center  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars Vedel","family":"Kessing","sequence":"additional","affiliation":[{"name":"Psychiatric Center Copenhagen, Faculty of Health and Medical Sciences Rigshospitalet, University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio A.","family":"Strejilevich","sequence":"additional","affiliation":[{"name":"Bipolar Disorder Program, Gerontopsychiatry Department, INECO Neurosciences Institute, Favaloro University  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soham","family":"Rej","sequence":"additional","affiliation":[{"name":"Division of Geriatric Psychiatry University of Toronto  Toronto Canada"},{"name":"Geri\u2010PARTy Research Group Jewish General Hospital, McGill University  Montreal Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shang\u2010Ying","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Taipei Medical University Hospital  Taipei Taiwan"},{"name":"Department of Psychiatry, School of Medicine, College of Medicine Taipei Medical University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariel G.","family":"Gildengers","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine  Pittsburgh PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osvaldo P.","family":"Almeida","sequence":"additional","affiliation":[{"name":"School of Psychiatry and Clinical Neurosciences &amp; Centre for Medical Research The University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth I.","family":"Shulman","sequence":"additional","affiliation":[{"name":"Geriatric Psychiatry, Faculty of Medicine Sunnybrook Health Sciences Centre, University of Toronto  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha","family":"Sajatovic","sequence":"additional","affiliation":[{"name":"Case Western Reserve University School of Medicine, University Hospitals Case Medical Center  Cleveland OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"The International Society for Bipolar Disorders Task Force for Older Adults with Bipolar Disorder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,7,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.114.145706"},{"key":"e_1_2_6_3_1","volume-title":"Gu\u00eda de Pr\u00e1ctica Cl\u00ednica sobre Trastorno Bipolar","author":"Asociaci\u00f3n Espa\u00f1ola de Neuropsiquiatria","year":"2012"},{"key":"e_1_2_6_4_1","unstructured":"AUGE.2013.Ministerio de Salud del Gobierno de Chile. 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