{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:28:49Z","timestamp":1761060529785,"version":"3.37.3"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T00:00:00Z","timestamp":1519603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30 AG028747","R01 AG029315","R37 AG009901","T32 AG000262"],"award-info":[{"award-number":["P30 AG028747","R01 AG029315","R37 AG009901","T32 AG000262"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Depression after hip fracture in older adults is associated with worse physical performance; however, depressive symptoms are dynamic, fluctuating during the recovery period. The study aim was to determine how the persistence of depressive symptoms over time cumulatively affects the recovery of physical performance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Marginal structural models estimated the cumulative effect of persistence of depressive symptoms on gait speed during hip fracture recovery among older adults (n\u00a0=\u00a0284) enrolled in the Baltimore Hip Studies 7th cohort. Depressive symptoms at baseline and at 2\u2010month and 6\u2010month postadmission for hip fracture were evaluated by using the Center for Epidemiological Studies Depression Scale, and persistence of symptoms was assessed as a time\u2010averaged severity lagged to standardized 3\u00a0m gait speed at 2, 6, and 12\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A 1\u2010unit increase in time\u2010averaged Center for Epidemiological Studies Depression score was associated with a mean difference in gait speed of \u22120.0076 standard deviations (95% confidence interval [CI]: \u22120.0184, 0.0032; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.166). The association was largest in magnitude from baseline to 6\u00a0months: \u22120.0144 standard deviations (95% CI: \u22120.0303, 0.0015; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.076). Associations for the other time intervals were smaller: \u22120.0028 standard deviations (95% CI: \u22120.0138, 0.0083; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.621) at 2\u00a0months and \u22120.0121 standard deviations (95% CI: \u22120.0324, 0.0082; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.238) at 12\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although not statistically significant, the magnitude of the numerical estimates suggests that expressing more depressive symptoms during the first 6\u00a0months after hip fracture has a meaningful impact on functional recovery.<\/jats:p><\/jats:sec>","DOI":"10.1002\/gps.4864","type":"journal-article","created":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T14:39:04Z","timestamp":1519655944000},"page":"875-882","source":"Crossref","is-referenced-by-count":9,"title":["Persistence of depressive symptoms and gait speed recovery in older adults after hip fracture"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3611-5494","authenticated-orcid":false,"given":"Alan M.","family":"Rathbun","sequence":"first","affiliation":[{"name":"Geriatric Research, Education and Clinical Center VA Maryland Health Care System  Baltimore MD USA"},{"name":"Department of Epidemiology and Public Health University of Maryland School of Medicine  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle D.","family":"Shardell","sequence":"additional","affiliation":[{"name":"Translational Gerontology Branch National Institutes on Aging  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth A.","family":"Stuart","sequence":"additional","affiliation":[{"name":"Department of Mental Health Johns Hopkins Bloomberg School of Public Health  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann 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