{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T02:10:46Z","timestamp":1771294246968,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,3,7]],"date-time":"2018-03-07T00:00:00Z","timestamp":1520380800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001697","name":"Keio University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001697","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005939","name":"Chiyoda Mutual Life Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005939","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005939","name":"Chiyoda Mutual Life Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005939","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001697","name":"Keio University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001697","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Despite a steady increase in life expectancy, a few studies have investigated cross\u2010sectional correlates and longitudinal predictors of cognitive function, a core domain of the successful aging, among socio\u2010clinico\u2010demographic factors in the oldest\u2010old exclusively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aims of this study were to examine socio\u2010clinico\u2010demographic characteristics associated with global cognition and its changes in the oldest\u2010old.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reanalyzed a dataset of cognitively preserved community\u2010dwelling subjects aged 85\u00a0years and older in the Tokyo Oldest Old Survey on Total Health, a 6\u2010year longitudinal observational study. This study consisted of (1) baseline cross\u2010sectional analyses examining correlates of global cognition (n\u00a0=\u00a0248) among socio\u2010clinico\u2010demographic factors and (2) longitudinal analyses examining baseline predictors for changes of global cognition in 3\u2010year follow\u2010up (n\u00a0=\u00a0195). The Mini\u2010Mental State Examination was used as a screening test to assess global cognition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At baseline, higher weights were related to higher cognitive function in the oldest\u2010old. The baseline predictors of global cognitive decline in 3\u2010year follow\u2010up were higher global cognition, shorter education period, and lower sociocultural activities and lower instrumental activity of daily living, in this order.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The present study suggests that it is crucial to attain higher education during early life and avoid leanness or obesity, participate in sociocultural cognitive activities during late life, and maintain instrumental activity of daily living to preserve optimal cognitive function in the oldest\u2010old, which will facilitate developing prevention strategies for cognitive decline and promoting successful aging in this increasing population.<\/jats:p><\/jats:sec>","DOI":"10.1002\/gps.4873","type":"journal-article","created":{"date-parts":[[2018,3,7]],"date-time":"2018-03-07T23:26:48Z","timestamp":1520465208000},"page":"926-933","source":"Crossref","is-referenced-by-count":7,"title":["Relationships between socio\u2010clinico\u2010demographic factors and global cognitive function in the oldest old living in the Tokyo Metropolitan area: Reanalysis of the Tokyo Oldest Old Survey on Total Health (TOOTH)"],"prefix":"10.1002","volume":"33","author":[{"given":"Yoko","family":"Eguchi","sequence":"first","affiliation":[{"name":"Department of Neuropsychiatry Keio University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kumiko","family":"Tasato","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry Keio University School of Medicine  Tokyo 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