{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T16:36:41Z","timestamp":1780331801218,"version":"3.54.1"},"reference-count":44,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T00:00:00Z","timestamp":1555891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30AG035982"],"award-info":[{"award-number":["P30AG035982"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Sexual minority discrimination might lead to a higher risk of mild cognitive impairment (MCI) and dementia. The aim of this study was to assess the risk of MCI and dementia between older adults in same\u2010sex relationships (SSR) and opposite\u2010sex relationships (OSR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed longitudinal data from the National Alzheimer's Coordinating Center up to September 2017. Analyses included cognitively normal individuals 55+ at baseline who had a spouse, partner, or companion as study partner at any assessment. Associations were calculated using survival analysis adjusting for demographics and APOE\u2010e4 carrier status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Hazard ratios of MCI and dementia did not differ statistically between SSR and OSR individuals in the total sample nor stratified by sex.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The lack of association between SSR and MCI and dementia warrants future research into their potential resilience mechanisms and the inclusion of sexual minority status questions in research and surveillance studies. The potential recruitment bias caused by nonprobabilistic sampling of the cohort and the reporting and ascertainment bias caused by using SSR to infer sexual minority status may have influenced our findings.<\/jats:p><\/jats:sec>","DOI":"10.1002\/gps.5092","type":"journal-article","created":{"date-parts":[[2019,3,13]],"date-time":"2019-03-13T05:18:36Z","timestamp":1552454316000},"page":"828-835","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Risk of dementia and mild cognitive impairment among older adults in same\u2010sex relationships"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1013-7847","authenticated-orcid":false,"given":"Jaime","family":"Perales\u2010Puchalt","sequence":"first","affiliation":[{"name":"Department of Neurology University of Kansas Alzheimer's Disease Center  Fairway KS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Gauthreaux","sequence":"additional","affiliation":[{"name":"National Alzheimer's Coordinating Center, Department of Epidemiology University of Washington  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Flatt","sequence":"additional","affiliation":[{"name":"Institute for Health &amp; Aging University of California, San Francisco  San Francisco CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merilee Ann","family":"Teylan","sequence":"additional","affiliation":[{"name":"National Alzheimer's Coordinating Center, Department of Epidemiology University of Washington  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Resendez","sequence":"additional","affiliation":[{"name":"LatinosAgainstAlzheimer's Coalition UsAgainstAlzheimer's  Chevy Chase MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8761-9014","authenticated-orcid":false,"given":"Walter A.","family":"Kukull","sequence":"additional","affiliation":[{"name":"National Alzheimer's Coordinating Center, Department of Epidemiology University of Washington  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwun C.G.","family":"Chan","sequence":"additional","affiliation":[{"name":"National Alzheimer's Coordinating Center, Department of Biostatistics University of Washington  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Burns","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Kansas Alzheimer's Disease Center  Fairway KS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric D.","family":"Vidoni","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Kansas Alzheimer's Disease Center  Fairway KS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0733464816672047"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/13607863.2016.1168362"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/00918369.2015.1088317"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/gnw100"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0164027516650003"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0733464815591210"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617712000628"},{"key":"e_1_2_10_9_1","article-title":"Perceived stress and cognitive decline in different cognitive domains in a cohort of older African Americans","author":"Turner AD","year":"2016","journal-title":"Am J Geriatr Psychiatry"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jagp.2016.11.002"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/WAD.0000000000000125"},{"key":"e_1_2_10_12_1","article-title":"Correlates of subjective cognitive decline in lesbian, gay, bisexual, and transgender older adults","volume":"2018","author":"Flatt JD","journal-title":"J Alzheimers Dis"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/WAD.0b013e318142774e"},{"key":"e_1_2_10_14_1","unstructured":"National Alzheimer's Coordinating Center.Uniform Data Set (UDS).2017.https:\/\/www.alz.washington.edu\/NONMEMBER\/NACCFormsAndDoc.html#javascript:void(0). 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