{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:09:47Z","timestamp":1790514587228,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,4,21]],"date-time":"2020-04-21T00:00:00Z","timestamp":1587427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Benzodiazepines and non\u2010benzodiazepine hypnotics (or Z\u2010drugs) (BZD\/Z) are widely prescribed for older patients despite major side effects and risks when chronically used. The patient's understanding of the treatment is one of the keys to good adherence. The purpose of the study was to assess the knowledge of BZD\/Z treatment among older people who were taking BZD\/Z for the long term by studying the concordance between the declared reason for taking BZD\/Z and its indication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a cross\u2010sectional, pharmacoepidemiologic ancillary of a national study. Data were collected through a semi\u2010structured interview. All patients from the main study were included. \u201cGood knowledge\u201d was considered when patients gave an indication for each BZD\/Z that was similar to its marketing authorisation. Univariate and multivariate analyses were carried out to adequately determine profiles and characterise associations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>More than half of the patients (61.6%) had a good knowledge regarding their treatment. The presence of a psychiatric disorder, a mean duration of BZD\/Z use of less than 120\u2009months, a desire to stop treatment, educational status and number and type of BZD\/Z used were significantly associated (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05) with good knowledge. In the multivariate analysis, only a psychiatric disorder, educational status and taking at least one hypnotic drug were associated with good knowledge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>At the time of shared medical decision, it appears essential to improve the knowledge of the treatment by the patient. The rate of patients with good knowledge of their BZD\/Z treatment remains low and even lower than what was previously found in the literature for other drug classes. In contrast to patients with good knowledge, these data highlight the characteristics of patients with poor knowledge of their BZD\/Z treatment, which may allow populations at risk to be targeted and enable education measures to be strengthened.<\/jats:p><\/jats:sec>","DOI":"10.1002\/gps.5307","type":"journal-article","created":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T04:30:13Z","timestamp":1586752213000},"page":"870-876","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Do older people know why they take benzodiazepines? A national French cross\u2010sectional survey of long\u2010term consumers"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7400-1212","authenticated-orcid":false,"given":"Edouard\u2010Jules","family":"Laforgue","sequence":"first","affiliation":[{"name":"Clinical Pharmacology Department Centre Hospitalier Universitaire de Nantes, University Hospital  Nantes France"},{"name":"Addictology and Liaison\u2010Psychiatry Department Centre Hospitalier Universitaire de Nantes, University Hospital  Nantes France"},{"name":"INSERM UMR 1246, SPHERE, Methods in Patients\u2010centered outcomes and Health Research Nantes and Tours University  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Jobert","sequence":"additional","affiliation":[{"name":"INSERM UMR 1246, SPHERE, Methods in Patients\u2010centered outcomes and Health Research Nantes and Tours University  Nantes France"},{"name":"Direction de la recherche Centre Hospitalier Universitaire de Nantes, University Hospital  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgane","family":"Rousselet","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology Department Centre Hospitalier Universitaire de Nantes, University Hospital  Nantes France"},{"name":"Addictology and Liaison\u2010Psychiatry Department Centre Hospitalier Universitaire de Nantes, University Hospital  Nantes France"},{"name":"INSERM UMR 1246, SPHERE, Methods in Patients\u2010centered outcomes and Health Research Nantes and Tours University  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Grall\u2010Bronnec","sequence":"additional","affiliation":[{"name":"Addictology and Liaison\u2010Psychiatry Department Centre Hospitalier Universitaire de Nantes, University Hospital  Nantes France"},{"name":"INSERM UMR 1246, SPHERE, Methods in Patients\u2010centered outcomes and Health Research Nantes and Tours University  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"FAN network","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Jolliet","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology Department Centre Hospitalier Universitaire de Nantes, University Hospital  Nantes France"},{"name":"INSERM UMR 1246, SPHERE, Methods in Patients\u2010centered outcomes and Health Research Nantes and Tours University  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanny","family":"Feuillet","sequence":"additional","affiliation":[{"name":"INSERM UMR 1246, SPHERE, Methods in Patients\u2010centered outcomes and Health Research Nantes and Tours University  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Victorri\u2010Vigneau","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology Department Centre Hospitalier Universitaire de Nantes, University Hospital  Nantes France"},{"name":"INSERM UMR 1246, SPHERE, Methods in Patients\u2010centered outcomes and Health Research Nantes and Tours University  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,21]]},"reference":[{"issue":"3","key":"e_1_2_10_2_1","first-page":"187","article-title":"Epidemiology of the use of anxiolytic and hypnotic drugs in France and in the world","volume":"22","author":"P\u00e9lissolo A","year":"1996","journal-title":"Encephale"},{"key":"e_1_2_10_3_1","first-page":"720","article-title":"Prescription m\u00e9dicamenteuse chez le sujet \u00e2g\u00e9","volume":"20","author":"Desplanques\u2010Leperre A","year":"2006","journal-title":"Rev Prat MG"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/10826084.2014.912226"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.55.3.233"},{"key":"e_1_2_10_6_1","unstructured":"BriotM.Rapport sur le bon usage des m\u00e9dicaments psychotropes.http:\/\/www.ladocumentationfrancaise.fr\/rapports-publics\/064000593\/index.shtml. 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