{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:43:48Z","timestamp":1786977828468,"version":"build-2736575974"},"reference-count":53,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T00:00:00Z","timestamp":1686787200000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001077","name":"Royal Brisbane and Women's Hospital Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001077","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018897","name":"Lions Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018897","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cognitive deficits are evident throughout the course of Parkinson's disease (PD), with 24% of patients experiencing subtle cognitive disturbances at the time of diagnosis, and with up to 80% of patients developing PD dementia (PDD) at advanced stages of the disease PD patients with mild cognitive impairment (MCI), an at\u2010risk phenotype of PDD, present with heterogeneous clinical characteristics that complicate the management of PD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aims to examine the characteristics of PD\u2010MCI by using the Movement Disorder Society (MDS) diagnostic criteria and evaluate the validity of global cognitive scales in identifying PD\u2010MCI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Seventy\u2010nine (79) PD patients completed neuropsychological assessments and a comprehensive cognitive battery. PD\u2010MCI was classified according to the level 2 MDS task force criteria. Mini\u2010Mental State Examination (sMMSE), Montreal Cognitive Assessment (MoCA) and Parkinson's Disease Cognitive Rating Scale (PDCRS) were examined against a level 2 dichotomised PD\u2010MCI diagnosis. Characteristics of PD\u2010MCI were evaluated using logistic regression analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010seven patients met criteria for PD\u2010MCI (34%). The MoCA and PDCRS demonstrated high validity to screen for PD\u2010MCI. Impairments in multiple cognitive domains were observed in 77.8% of PD\u2010MCI patients. There were significantly more males in the PD\u2010MCI group compared to PD patients without MCI (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PD patients with MCI exhibited impairments in the attention\/working memory, executive function and memory domains. Heterogeneous cognitive characteristics in PD warrant further investigation into specific cognitive subtypes to advance understanding and effective evaluation of PD\u2010MCI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/gps.5955","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T08:16:21Z","timestamp":1686816981000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Global assessment, cognitive profile, and characteristics of mild cognitive impairment in Parkinson's disease"],"prefix":"10.1002","volume":"38","author":[{"given":"Jihyun","family":"Yang","sequence":"first","affiliation":[{"name":"UQ Centre for Clinical Research Faculty of Medicine The University of Queensland  Herston Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Pourzinal","sequence":"additional","affiliation":[{"name":"UQ Centre for Clinical 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