{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:28:16Z","timestamp":1785544096595,"version":"3.56.0"},"reference-count":37,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Geriat Psychiatry"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Treating insomnia with hypnotic drugs in elderly patients has many adverse effects. This study aims to assess the effect of two discontinuation methods of hypnotic drugs during acute hospitalization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted an open\u2010label randomized controlled trial that included participants aged 60 and above taking benzodiazepines or Z\u2010Drugs for at least 3\u00a0months as a treatment for insomnia and were admitted to the hospital. In the prospective arm, patients were randomly assigned into two intervention groups. In the Minimal Intervention (MI) group, patients received an explanation of the dangers of long\u2010term treatment and a recommendation to stop the treatment. In the Tapering Down Intervention (TDI) group, in addition to the explanation, patients received a tapering down table. In the retrospective arm (control group), we examined the use of hypnotic drugs among hospitalized patients 3\u00a0months after hospitalization, similar to the patients in the prospective arm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>46 patients were enrolled in the MI group, 55 patients in the TDI group, and 114 patients in the control group. The mean age in the three groups was 75.0\u00a0\u00b1\u00a08.2, 75.9\u00a0\u00b1\u00a09.0, and 75.0\u00a0\u00b1\u00a07.9\u00a0years respectively (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.85). After 3\u00a0months, seven (15.2%) of the patients in the MI group, 15 (27.3%) in the TD group, and 2 (1.8%) in the control group (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.00003) were weaned from the hypnotic drugs treatment, without a significant difference between the intervention groups (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.221).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A short intervention during hospitalization results in a significant decrease in hypnotic drug use.<\/jats:p><\/jats:sec>","DOI":"10.1002\/gps.6012","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T01:34:38Z","timestamp":1697074478000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Discontinuation of benzodiazepines and Z\u2010drugs in hospitalised population at the age of 60 and above. 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