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By integrating recent advances in molecular biology, neuroimaging and clinical psychology, this review highlights the epidemiological characteristics, neurobiological mechanisms, clinical manifestations and treatment challenges of PTSD in both UAV operators and ground troops affected by UAV activities. By providing a comprehensive perspective on the mental health issues stemming from this novel mode of warfare, this article aims to inform the development of targeted prevention and intervention strategies to better support the psychological resilience of military personnel in the era of unmanned combat.<\/jats:p>","DOI":"10.1002\/gps3.70050","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T07:23:14Z","timestamp":1787815394000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Application of unmanned aerial vehicles in modern battlefields and their impact on post\u2010traumatic stress disorder in military personnel: A review"],"prefix":"10.1002","volume":"39","author":[{"given":"Yu","family":"Xue","sequence":"first","affiliation":[{"name":"Department of Medical Service The 960th Hospital of the PLA Joint Logistics Support Force  Jinan Shandong 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