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The field of precision medicine continues to grapple with how to best serve disability communities. In this paper, we suggest that precision medicine faces an ethical tension between its goal to treat or cure disabling conditions and views that consider disability as a marginalized identity. We appeal to the concepts of recognition justice and distributive justice to argue that the ELSI community should take a more proactive role in promoting disability inclusion in precision medicine's practice and research. We also highlight two priorities for the ELSI community moving forward: facilitating greater collaboration between genetics and genomic professionals and disability communities and advocating for inclusive research design and disability accommodations in the research process.<\/jats:p>","DOI":"10.1002\/hast.4928","type":"journal-article","created":{"date-parts":[[2024,12,21]],"date-time":"2024-12-21T14:00:17Z","timestamp":1734789617000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Nothing about Us without Us in Precision Medicine: A Call to Reframe Disability Difference in Genetics and Genomics"],"prefix":"10.1002","volume":"54","author":[{"given":"Kevin T.","family":"Mintz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph A.","family":"Stramondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly K.","family":"Tabor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,21]]},"reference":[{"key":"e_1_2_7_1_1","unstructured":"National Institutes of Health \u201cNIH Designates People with Disabilities as a Population with Health Disparities \u201d"},{"key":"e_1_2_7_1_2","unstructured":"U.S. Department of Health & Human Services National Institutes of Health news release September 26 2023 https:\/\/www.nih.gov\/news-events\/news-releases\/nih-designates-people-disabilities-population-health-disparities."},{"key":"e_1_2_7_2_1","unstructured":"\u201cRequest for Information (RFI): Inviting Comments and Suggestions on Updating the NIH Mission Statement \u201d NOT\u2010OD\u201023\u2010163 National Institutes of Health August 25 2023 https:\/\/grants.nih.gov\/grants\/guide\/notice-files\/NOT-OD-23-163.html."},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511614590.005"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780198732587.001.0001"},{"key":"e_1_2_7_3_3","unstructured":"A.Silvers \u201cA Fatal Attraction to Normalizing: Treating Disabilities as Deviations from \u2018Species\u2010Typical\u2019 Functioning \u201d inEnhancing Human Traits: Ethical and Social Implications ed. 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