{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T11:06:10Z","timestamp":1775127970743,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2017,7,26]],"date-time":"2017-07-26T00:00:00Z","timestamp":1501027200000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hastings Center Report"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Decades of globally coordinated work in conservation have failed to slow the loss of biodiversity. To do better\u2014even if that means nothing more than failing less spectacularly\u2014bolder thinking is necessary. One of the first possible conservation applications of synthetic biology to be debated is the use of genetic tools to resurrect once\u2010extinct species. Since the currency of conservation is biodiversity and the discipline of conservation biology was formed around the prevention of species extinctions, the prospect of reversing extinctions might have been expected to generate unreserved enthusiasm. But it was not universal acclaim that greeted the coming\u2010out party for \u201cde\u2010extinction\u201d that was the TEDx conference and accompanying<\/jats:italic> National Geographic <jats:italic>feature in 2013. Why the concern, the skepticism, even the hostility among many conservationists about the idea of restoring lost species? And how does this professional concern relate to public perception and support for conservation? This essay explores the barriers to the acceptance of risky new genomic\u2010based conservation tools by considering five key areas and associated questions that could be addressed in relation to any new conservation tool. I illustrate these using the specific example of de\u2010extinction, and in doing so, I consider whether de\u2010extinction would necessarily be the best first point of engagement between conservation biology and synthetic biology.<\/jats:italic><\/jats:p>","DOI":"10.1002\/hast.745","type":"journal-article","created":{"date-parts":[[2017,7,26]],"date-time":"2017-07-26T16:53:04Z","timestamp":1501087984000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["De\u2010extinction and Barriers to the Application of New Conservation Tools"],"prefix":"10.1002","volume":"47","author":[{"given":"Philip J.","family":"Seddon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,7,26]]},"reference":[{"key":"e_1_2_2_1_1","unstructured":"ETC Group Reckless Driving\u2014Gene Drives and the End of Nature http:\/\/www.etcgroup.org\/content\/reckless-driving-gene-drives-and-end-nature."},{"key":"e_1_2_2_2_1","unstructured":"TEDx DeExtinction March 15 2013 https:\/\/www.ted.com\/topics\/deextinction;"},{"key":"e_1_2_2_2_2","article-title":"Opinion: The Case against Species Revival","author":"Pimm S.","year":"2013","journal-title":"National Geographic News"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.350.6265.1144"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1365-2435.12705"},{"key":"e_1_2_2_5_1","unstructured":"Ibid."},{"issue":"1","key":"e_1_2_2_6_1","first-page":"11","article-title":"The Perils of De\u2010extinction","volume":"8","author":"Minteer B. 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