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The underlying neural substrates of these episodic memory deficits, however, likely differ contingent on dementia type. In this study we sought to elucidate the neural substrates of episodic memory performance, across recall and recognition tasks, in both patient groups using voxel\u2010based morphometry (VBM) analyses. We predicted that episodic memory dysfunction would be apparent in both patient groups but would relate to divergent patterns of neural atrophy specific to each dementia type. We assessed episodic memory, across verbal and visual domains, in 19 bvFTD, 18 AD patients, and 19 age\u2010 and education\u2010matched controls. Behaviorally, patient groups were indistinguishable for immediate and delayed recall, across verbal and visual domains. Whole\u2010brain VBM analyses revealed regions commonly implicated in episodic retrieval across groups, namely the right temporal pole, right frontal lobe, left paracingulate gyrus, and right anterior hippocampus. Divergent neural networks specific to each group were also identified. Whereas a widespread network including posterior regions such as the posterior cingulate cortex, parietal and occipital cortices was exclusively implicated in AD, the frontal and anterior temporal lobes underpinned the episodic memory deficits in bvFTD. Our results point to distinct neural changes underlying episodic memory decline specific to each dementia syndrome. <jats:italic>Hum Brain Mapp 35:1422\u20131435, 2014<\/jats:italic>. \u00a9 201 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/hbm.22263","type":"journal-article","created":{"date-parts":[[2013,5,14]],"date-time":"2013-05-14T11:50:51Z","timestamp":1368532251000},"page":"1422-1435","source":"Crossref","is-referenced-by-count":157,"title":["Common and unique gray matter correlates of episodic memory dysfunction in frontotemporal dementia and alzheimer's disease"],"prefix":"10.1002","volume":"35","author":[{"given":"Muireann","family":"Irish","sequence":"first","affiliation":[{"name":"Neuroscience Research Australia, Barker Street, Randwick, Sydney, Australia"},{"name":"School of Medical Sciences, University of New South Wales, Sydney, Australia"},{"name":"ARC Centre of Excellence in Cognition and its Disorders, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Piguet","sequence":"additional","affiliation":[{"name":"Neuroscience Research Australia, Barker Street, Randwick, Sydney, Australia"},{"name":"School of Medical Sciences, University of New South Wales, Sydney, Australia"},{"name":"ARC Centre of Excellence in Cognition and its Disorders, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Hodges","sequence":"additional","affiliation":[{"name":"Neuroscience Research Australia, Barker Street, Randwick, Sydney, Australia"},{"name":"School of Medical Sciences, University of New South Wales, Sydney, Australia"},{"name":"ARC Centre of Excellence in Cognition and its Disorders, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Hornberger","sequence":"additional","affiliation":[{"name":"Neuroscience Research Australia, Barker Street, Randwick, Sydney, Australia"},{"name":"School of Medical Sciences, University of New South Wales, Sydney, Australia"},{"name":"ARC Centre of Excellence in Cognition and its Disorders, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,5,14]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Non\u2010linear optimisation. 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